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Article: Short communication: Absence of HIV infection in the choroid plexus of two patients who died rapidly with HIV-associated dementia

TitleShort communication: Absence of HIV infection in the choroid plexus of two patients who died rapidly with HIV-associated dementia
Authors
Issue Date2008
Citation
AIDS Research and Human Retroviruses, 2008, v. 24, n. 6, p. 839-843 How to Cite?
AbstractAbsence of HIV infection of the choroid plexus (CPx) and macrophages in choroidal stroma was observed in two HIV-infected individuals who died 7 weeks and 12 months following the onset of HIV encephalitis. In contrast, the profound macrophage-related pathology associated with HIV infection presented in other neural tissue from 48 brain regions (seven CPx) was analyzed. These data suggest that HIV entry to the CNS may be independent of the CPx. It also emphasizes that the CPx is unlikely to harbor a significant reservoir of HIV in patients who rapidly progress to dementia. © 2008 Mary Ann Liebert, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/207059
ISSN
2015 Impact Factor: 1.949
2015 SCImago Journal Rankings: 1.024

 

DC FieldValueLanguage
dc.contributor.authorZhou, Li-
dc.contributor.authorNg, Thomas-
dc.contributor.authorYuksel, Aysen-
dc.contributor.authorWang, Bin-
dc.contributor.authorDwyer, Dominic Edmund-
dc.contributor.authorSaksena, Nitin Kumar-
dc.date.accessioned2014-12-09T04:31:19Z-
dc.date.available2014-12-09T04:31:19Z-
dc.date.issued2008-
dc.identifier.citationAIDS Research and Human Retroviruses, 2008, v. 24, n. 6, p. 839-843-
dc.identifier.issn0889-2229-
dc.identifier.urihttp://hdl.handle.net/10722/207059-
dc.description.abstractAbsence of HIV infection of the choroid plexus (CPx) and macrophages in choroidal stroma was observed in two HIV-infected individuals who died 7 weeks and 12 months following the onset of HIV encephalitis. In contrast, the profound macrophage-related pathology associated with HIV infection presented in other neural tissue from 48 brain regions (seven CPx) was analyzed. These data suggest that HIV entry to the CNS may be independent of the CPx. It also emphasizes that the CPx is unlikely to harbor a significant reservoir of HIV in patients who rapidly progress to dementia. © 2008 Mary Ann Liebert, Inc.-
dc.languageeng-
dc.relation.ispartofAIDS Research and Human Retroviruses-
dc.titleShort communication: Absence of HIV infection in the choroid plexus of two patients who died rapidly with HIV-associated dementia-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1089/aid.2007.0147-
dc.identifier.pmid18544025-
dc.identifier.scopuseid_2-s2.0-45749090991-
dc.identifier.volume24-
dc.identifier.issue6-
dc.identifier.spage839-
dc.identifier.epage843-

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