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Article: Pigmented central neurocytoma: Case report and literature review

TitlePigmented central neurocytoma: Case report and literature review
Authors
KeywordsNeuromelanin
Pigmented central neurocytoma
Melanin
Lipofuscin
Issue Date1999
Citation
American Journal of Surgical Pathology, 1999, v. 23, n. 9, p. 1136-1140 How to Cite?
AbstractA case of pigmented central neurocytoma is reported. The tumor showed histologic, immunophenotypic, and ultrastructural features of central neurocytoma. The pigment consisted of an intimate association of lipofuscin and neuromelanin. Pigmented neuroepithelial tumors are rare, and the pigments may be neuromelanin or melanin. Pigmented central neurocytoma has not been described to date. The low proliferation rate of the tumor suggests a delayed turnover of tumor cells as a possible cause of lipofuscin accumulation. Autocatalytic peroxidation of lipofuscin is a possible mechanism of neuromelanin formation.
Persistent Identifierhttp://hdl.handle.net/10722/206995
ISSN
2015 Impact Factor: 4.951
2015 SCImago Journal Rankings: 2.393

 

DC FieldValueLanguage
dc.contributor.authorNg, Thomas-
dc.contributor.authorWong, Angela Y.-
dc.contributor.authorBoadle, Ross A.-
dc.contributor.authorCompton, Jeffrey S.-
dc.date.accessioned2014-12-09T04:31:12Z-
dc.date.available2014-12-09T04:31:12Z-
dc.date.issued1999-
dc.identifier.citationAmerican Journal of Surgical Pathology, 1999, v. 23, n. 9, p. 1136-1140-
dc.identifier.issn0147-5185-
dc.identifier.urihttp://hdl.handle.net/10722/206995-
dc.description.abstractA case of pigmented central neurocytoma is reported. The tumor showed histologic, immunophenotypic, and ultrastructural features of central neurocytoma. The pigment consisted of an intimate association of lipofuscin and neuromelanin. Pigmented neuroepithelial tumors are rare, and the pigments may be neuromelanin or melanin. Pigmented central neurocytoma has not been described to date. The low proliferation rate of the tumor suggests a delayed turnover of tumor cells as a possible cause of lipofuscin accumulation. Autocatalytic peroxidation of lipofuscin is a possible mechanism of neuromelanin formation.-
dc.languageeng-
dc.relation.ispartofAmerican Journal of Surgical Pathology-
dc.subjectNeuromelanin-
dc.subjectPigmented central neurocytoma-
dc.subjectMelanin-
dc.subjectLipofuscin-
dc.titlePigmented central neurocytoma: Case report and literature review-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00000478-199909000-00019-
dc.identifier.pmid10478676-
dc.identifier.scopuseid_2-s2.0-0032840788-
dc.identifier.volume23-
dc.identifier.issue9-
dc.identifier.spage1136-
dc.identifier.epage1140-

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