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postgraduate thesis: Diffusion tensor imaging of the cervical spinal cord in Chinese healthy population

TitleDiffusion tensor imaging of the cervical spinal cord in Chinese healthy population
Authors
Issue Date2014
PublisherThe University of Hong Kong (Pokfulam, Hong Kong)
Citation
Chan, T. [陳天恩]. (2014). Diffusion tensor imaging of the cervical spinal cord in Chinese healthy population. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5318896
AbstractMagnetic Resonance Imaging (MRI) has been applied in diagnosing Cervical Spondylosis Myelopathy (CSM) clinically. However, morphometric and signal change of MRI have not shown consistent relations with neurological function or outcome after surgical intervention. Diffusion Tensor Imaging (DTI) is an advanced MRI technology, which uses the principle of anisotropic water diffusion property. Recent studies indicated that DTI could be used as diagnostic tools for Cervical Spondylosis Myelopathy (CSM). The study aims to establish a Region of Interest (ROI)-based database. 65 healthy Chinese subjects were recruited for functional MR scanning. The effects on age and gender would also be investigated. Whole cord FA values decreased from upper cord level to lower cord level. White matter FA and AD values are significant higher than grey matter. White matter RD values are significant lower than grey matter. MD values of whole cord, white matter and grey matter are similar. There are no significant differences (P>0.05) of DTI metrics between males and females. There are significant differences (P<0.05) of DTI metrics in cervical spinal cord white matter in advancing age.
DegreeMaster of Medical Sciences
SubjectSpinal cord - Magnetic resonance imaging
Dept/ProgramOrthopaedics and Traumatology
Persistent Identifierhttp://hdl.handle.net/10722/206563

 

DC FieldValueLanguage
dc.contributor.authorChan, Tin-yan-
dc.contributor.author陳天恩-
dc.date.accessioned2014-11-19T23:15:29Z-
dc.date.available2014-11-19T23:15:29Z-
dc.date.issued2014-
dc.identifier.citationChan, T. [陳天恩]. (2014). Diffusion tensor imaging of the cervical spinal cord in Chinese healthy population. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5318896-
dc.identifier.urihttp://hdl.handle.net/10722/206563-
dc.description.abstractMagnetic Resonance Imaging (MRI) has been applied in diagnosing Cervical Spondylosis Myelopathy (CSM) clinically. However, morphometric and signal change of MRI have not shown consistent relations with neurological function or outcome after surgical intervention. Diffusion Tensor Imaging (DTI) is an advanced MRI technology, which uses the principle of anisotropic water diffusion property. Recent studies indicated that DTI could be used as diagnostic tools for Cervical Spondylosis Myelopathy (CSM). The study aims to establish a Region of Interest (ROI)-based database. 65 healthy Chinese subjects were recruited for functional MR scanning. The effects on age and gender would also be investigated. Whole cord FA values decreased from upper cord level to lower cord level. White matter FA and AD values are significant higher than grey matter. White matter RD values are significant lower than grey matter. MD values of whole cord, white matter and grey matter are similar. There are no significant differences (P>0.05) of DTI metrics between males and females. There are significant differences (P<0.05) of DTI metrics in cervical spinal cord white matter in advancing age.-
dc.languageeng-
dc.publisherThe University of Hong Kong (Pokfulam, Hong Kong)-
dc.relation.ispartofHKU Theses Online (HKUTO)-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsThe author retains all proprietary rights, (such as patent rights) and the right to use in future works.-
dc.subject.lcshSpinal cord - Magnetic resonance imaging-
dc.titleDiffusion tensor imaging of the cervical spinal cord in Chinese healthy population-
dc.typePG_Thesis-
dc.identifier.hkulb5318896-
dc.description.thesisnameMaster of Medical Sciences-
dc.description.thesislevelMaster-
dc.description.thesisdisciplineOrthopaedics and Traumatology-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.5353/th_b5318896-

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