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Conference Paper: N-Acetylcysteine enhances cardiac HO-1 protein expression and antioxidant capacity in diabetic rats

TitleN-Acetylcysteine enhances cardiac HO-1 protein expression and antioxidant capacity in diabetic rats
Authors
Issue Date2010
Citation
The 2010 Annual Meeting of the American Society of Anesthesiologists (ASA), San Diego, CA., 16-20 October 2010. In Conference Proceedings, 2010, abstarct no. A1604 How to Cite?
AbstractINTRODUCTION: The antioxidant N-acetylcysteine (NAC) restores volatile anesthetic isoflurane-induced preconditioning against myocardial infarction in hyperglycemia (1). However, the mechanism whereby NAC restores isoflurane preconditioning cardioprotection is unclear. Elevated heme oxygenase-1 (HO-1) leads to improved postischaemic cardiac function in type 1 diabetes (2), and enhancement of cardiac antioxidant capacity facilitates postischemic myocardial functional recovery (3). Therefore, we hypothesized that NAC …
DescriptionAbstract no. A1604
Persistent Identifierhttp://hdl.handle.net/10722/206408

 

DC FieldValueLanguage
dc.contributor.authorMao, X-
dc.contributor.authorNg, JKF-
dc.contributor.authorIrwin, MG-
dc.contributor.authorVanhoutte, PMGR-
dc.contributor.authorXia, Z-
dc.date.accessioned2014-10-30T03:17:42Z-
dc.date.available2014-10-30T03:17:42Z-
dc.date.issued2010-
dc.identifier.citationThe 2010 Annual Meeting of the American Society of Anesthesiologists (ASA), San Diego, CA., 16-20 October 2010. In Conference Proceedings, 2010, abstarct no. A1604-
dc.identifier.urihttp://hdl.handle.net/10722/206408-
dc.descriptionAbstract no. A1604-
dc.description.abstractINTRODUCTION: The antioxidant N-acetylcysteine (NAC) restores volatile anesthetic isoflurane-induced preconditioning against myocardial infarction in hyperglycemia (1). However, the mechanism whereby NAC restores isoflurane preconditioning cardioprotection is unclear. Elevated heme oxygenase-1 (HO-1) leads to improved postischaemic cardiac function in type 1 diabetes (2), and enhancement of cardiac antioxidant capacity facilitates postischemic myocardial functional recovery (3). Therefore, we hypothesized that NAC …-
dc.languageeng-
dc.relation.ispartofProceedings of the 2010 Annual Meeting of the American Society Anesthesiologists-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleN-Acetylcysteine enhances cardiac HO-1 protein expression and antioxidant capacity in diabetic ratsen_US
dc.typeConference_Paperen_US
dc.identifier.emailMao, X: h0994071@hkusuc.hku.hk-
dc.identifier.emailNg, JKF: jkfng@hku.hk-
dc.identifier.emailIrwin, MG: mgirwin@hku.hk-
dc.identifier.emailVanhoutte, PMGR: vanhoutt@hku.hk-
dc.identifier.emailXia, Z: zhengyuan_xia@yahoo.com-
dc.description.naturepostprint-
dc.identifier.hkuros171210-
dc.publisher.placeUnited States-

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