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Article: Little girl who conquered the 'ALPPS'

TitleLittle girl who conquered the 'ALPPS'
Authors
KeywordsHepatoblastoma
In-situ split
Associating liver partition and portal vein ligation for stage hepatectomy
Portal vein
Hepatectomy
Issue Date2014
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal of Gastroenterology, 2014, v. 20 n. 29, p. 10208-10211 How to Cite?
Abstract© 2014 Baishideng Publishing Group Inc. All rights reserved. An insufficient future liver remnant (FLR) is associated with post-hepatectomy liver failure. Associating liver partition and portal vein ligation for stage hepatectomy (ALPPS) has been shown to be effective for the induction of rapid FLR hypertrophy so as to improve the resectability in patients with insufficient FLR. We hereby report our experience of this novel approach for a 6-year-old patient with hepatoblastoma. Computed tomography showed a hepatoblastoma measuring 12.5 cm x 9.9 cm x 11.7 cm in the right liver (Couinaud segment IV, V and VIII). Volumetric assessment of the FLR i.e., left lateral section was 112.6 mL i.e., 21.2% of the estimated total liver volume. In view of the small-for-size FLR, ALPPS was contemplated. An anterior approach was adopted for the in-situ parenchymal split without mobilisation of the right liver. FLR volumetry on the seventh postoperative day was 160.7 mL, which represented a 46.1% gain in volume, and a FLR/ESLV ratio of 30.2%. A right trisectionectomy was performed on the eighth postoperative day. Postoperative recovery was uneventful. Patient was discharged on day 16 after the first operation. To our knowledge, this was the first report that showed the applicability of ALPPS to a paediatric patient.
Persistent Identifierhttp://hdl.handle.net/10722/205971
ISSN
2015 Impact Factor: 2.787
2015 SCImago Journal Rankings: 1.076
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorChan, ACYen_US
dc.contributor.authorChung, HYen_US
dc.contributor.authorPoon, RTPen_US
dc.date.accessioned2014-10-20T10:37:59Z-
dc.date.available2014-10-20T10:37:59Z-
dc.date.issued2014en_US
dc.identifier.citationWorld Journal of Gastroenterology, 2014, v. 20 n. 29, p. 10208-10211en_US
dc.identifier.issn1007-9327en_US
dc.identifier.urihttp://hdl.handle.net/10722/205971-
dc.description.abstract© 2014 Baishideng Publishing Group Inc. All rights reserved. An insufficient future liver remnant (FLR) is associated with post-hepatectomy liver failure. Associating liver partition and portal vein ligation for stage hepatectomy (ALPPS) has been shown to be effective for the induction of rapid FLR hypertrophy so as to improve the resectability in patients with insufficient FLR. We hereby report our experience of this novel approach for a 6-year-old patient with hepatoblastoma. Computed tomography showed a hepatoblastoma measuring 12.5 cm x 9.9 cm x 11.7 cm in the right liver (Couinaud segment IV, V and VIII). Volumetric assessment of the FLR i.e., left lateral section was 112.6 mL i.e., 21.2% of the estimated total liver volume. In view of the small-for-size FLR, ALPPS was contemplated. An anterior approach was adopted for the in-situ parenchymal split without mobilisation of the right liver. FLR volumetry on the seventh postoperative day was 160.7 mL, which represented a 46.1% gain in volume, and a FLR/ESLV ratio of 30.2%. A right trisectionectomy was performed on the eighth postoperative day. Postoperative recovery was uneventful. Patient was discharged on day 16 after the first operation. To our knowledge, this was the first report that showed the applicability of ALPPS to a paediatric patient.-
dc.languageengen_US
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htmen_US
dc.relation.ispartofWorld Journal of Gastroenterologyen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectHepatoblastoma-
dc.subjectIn-situ split-
dc.subjectAssociating liver partition and portal vein ligation for stage hepatectomy-
dc.subjectPortal vein-
dc.subjectHepatectomy-
dc.titleLittle girl who conquered the 'ALPPS'en_US
dc.typeArticleen_US
dc.identifier.emailChan, ACY: acchan@hku.hken_US
dc.identifier.emailPoon, RTP: poontp@hku.hken_US
dc.identifier.authorityChan, ACY=rp00310en_US
dc.identifier.authorityChung, HY=rp02002en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3748/wjg.v20.i29.10208-
dc.identifier.pmid25110450-
dc.identifier.pmcidPMC4123352-
dc.identifier.scopuseid_2-s2.0-84905845193-
dc.identifier.hkuros240827en_US
dc.identifier.volume20en_US
dc.identifier.issue29en_US
dc.identifier.spage10208en_US
dc.identifier.epage10211en_US
dc.publisher.placeChinaen_US

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