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Article: Monoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity

TitleMonoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity
Authors
Issue Date2014
Citation
Fitoterapia, 2014, v. 98c, p. 124-129 How to Cite?
AbstractAn unusual nor-monoterpene with only nine carbons, nor-paeonilactone (1), two new monoterpenes, paeonisuffrone C (2), paeonilactone D (9), and a new monoterpene glucoside, paeonin D (3), along with ten known compounds were isolated from the dried roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR, and computational data. Compounds 4-14 were evaluated for their anti-proliferative activities against BT 483 human breast cancer cells and OVCA 429 human ovarian cancer cells by MTT assay.
Persistent Identifierhttp://hdl.handle.net/10722/204933

 

DC FieldValueLanguage
dc.contributor.authorLi, Pen_US
dc.contributor.authorZhang, ZMen_US
dc.contributor.authorLi, Ten_US
dc.contributor.authorZhang, Yen_US
dc.contributor.authorSze, CWen_US
dc.contributor.authorWang, GCen_US
dc.contributor.authorLi, YLen_US
dc.contributor.authorYe, WCen_US
dc.date.accessioned2014-09-20T01:10:38Z-
dc.date.available2014-09-20T01:10:38Z-
dc.date.issued2014en_US
dc.identifier.citationFitoterapia, 2014, v. 98c, p. 124-129en_US
dc.identifier.urihttp://hdl.handle.net/10722/204933-
dc.description.abstractAn unusual nor-monoterpene with only nine carbons, nor-paeonilactone (1), two new monoterpenes, paeonisuffrone C (2), paeonilactone D (9), and a new monoterpene glucoside, paeonin D (3), along with ten known compounds were isolated from the dried roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR, and computational data. Compounds 4-14 were evaluated for their anti-proliferative activities against BT 483 human breast cancer cells and OVCA 429 human ovarian cancer cells by MTT assay.en_US
dc.languageengen_US
dc.relation.ispartofFitoterapiaen_US
dc.titleMonoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activityen_US
dc.typeArticleen_US
dc.identifier.emailZhang, Y: ybzhang@hku.hken_US
dc.identifier.emailSze, CW: stephens@hku.hken_US
dc.identifier.authorityZhang, Y=rp01410en_US
dc.identifier.authoritySze, CW=rp00514en_US
dc.identifier.hkuros238932en_US
dc.identifier.volume98cen_US
dc.identifier.spage124en_US
dc.identifier.epage129en_US

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