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Conference Paper: Survival analysis of pancreaticoduodectomy with vascular reconstruction

TitleSurvival analysis of pancreaticoduodectomy with vascular reconstruction
Authors
Issue Date2013
Citation
The International Surgical Week (ISW 2013), Helsinki, Finland, 25-29 August 2013, p. abstract no. 296 How to Cite?
AbstractIntroduction: Pancreatic carcinoma and periamullary adenocarcinoma with invasion to portalvein(PV)or superiormesentericvein(SMV) or superiormesentericartery(SMA) are not uncommon. It this study, we aim to analyze the outcome and survival of pacreaticoduodenectomy with en bloc vascular resection. Material and Methods: Between January 2011 and December 2011, 146 patients received pancreaticoduodenectomy for adenocarcinoma in Department of surgery, Queen Mary Hospital, the University of Hong Kong. 101 patients received standard pancreaticoduodenectomy (group 1) and 35 patients received pancreaticoduodenectomy with en bloc resection of PV/SMV/SMA (group 2) and reconstruction. The immediate surgical outcome and survival were compared. The outcome of another 56 patients with borderline resectable Ca pancreas who received bypass surgery alone (group 3) was compared. Results: The median blood loss was 800ml (range 170ml-2500ml) in group 1 vs 1250ml (range100ml-5000ml) in group 2(p=0.0005).The median operation time was 570 minutes (range 380 to 917 minutes) in group1 vs 710 minutes (range 449 to 992 minutes)in group2 (p<0.0001).The 1 year,3 yearand fiver year overallsurvival forgroup1 patients was 77.8%,48.2% and 33%. The 1 year, 3 year and fiver year overall survival for group 2 patients was 69.4%,35.8% and 23.9%.(p=0.161). Ingroup 3, the 1 year and 3 year survival was 11.1% and 0%. (p< 0.0001) Conclusions: Pancreaticoduodenectomy with en bloc vascular resection is a safe treatment for locally advanced adenocarcinoma of the pancreas and periampullary region. It offers patients a better chance of survival compared to palliative bypass procedure.
DescriptionConference Theme: Connecting surgeons
Poster Presentation
Specific Field: Hepatobiliary and Pancreas Surgery
The abstract can be viewed at: http://flippingbook.nuboprepress.com/isw2013/web/
Persistent Identifierhttp://hdl.handle.net/10722/204477

 

DC FieldValueLanguage
dc.contributor.authorCheung, TTen_US
dc.contributor.authorPoon, RTPen_US
dc.contributor.authorChok, KSHen_US
dc.contributor.authorChan, ACYen_US
dc.contributor.authorDai, WC-
dc.contributor.authorChan, SC-
dc.contributor.authorFan, ST-
dc.contributor.authorLo, CM-
dc.date.accessioned2014-09-19T23:57:01Z-
dc.date.available2014-09-19T23:57:01Z-
dc.date.issued2013en_US
dc.identifier.citationThe International Surgical Week (ISW 2013), Helsinki, Finland, 25-29 August 2013, p. abstract no. 296en_US
dc.identifier.urihttp://hdl.handle.net/10722/204477-
dc.descriptionConference Theme: Connecting surgeons-
dc.descriptionPoster Presentation-
dc.descriptionSpecific Field: Hepatobiliary and Pancreas Surgery-
dc.descriptionThe abstract can be viewed at: http://flippingbook.nuboprepress.com/isw2013/web/-
dc.description.abstractIntroduction: Pancreatic carcinoma and periamullary adenocarcinoma with invasion to portalvein(PV)or superiormesentericvein(SMV) or superiormesentericartery(SMA) are not uncommon. It this study, we aim to analyze the outcome and survival of pacreaticoduodenectomy with en bloc vascular resection. Material and Methods: Between January 2011 and December 2011, 146 patients received pancreaticoduodenectomy for adenocarcinoma in Department of surgery, Queen Mary Hospital, the University of Hong Kong. 101 patients received standard pancreaticoduodenectomy (group 1) and 35 patients received pancreaticoduodenectomy with en bloc resection of PV/SMV/SMA (group 2) and reconstruction. The immediate surgical outcome and survival were compared. The outcome of another 56 patients with borderline resectable Ca pancreas who received bypass surgery alone (group 3) was compared. Results: The median blood loss was 800ml (range 170ml-2500ml) in group 1 vs 1250ml (range100ml-5000ml) in group 2(p=0.0005).The median operation time was 570 minutes (range 380 to 917 minutes) in group1 vs 710 minutes (range 449 to 992 minutes)in group2 (p<0.0001).The 1 year,3 yearand fiver year overallsurvival forgroup1 patients was 77.8%,48.2% and 33%. The 1 year, 3 year and fiver year overall survival for group 2 patients was 69.4%,35.8% and 23.9%.(p=0.161). Ingroup 3, the 1 year and 3 year survival was 11.1% and 0%. (p< 0.0001) Conclusions: Pancreaticoduodenectomy with en bloc vascular resection is a safe treatment for locally advanced adenocarcinoma of the pancreas and periampullary region. It offers patients a better chance of survival compared to palliative bypass procedure.-
dc.languageengen_US
dc.relation.ispartofInternational Surgical Week (ISW)en_US
dc.titleSurvival analysis of pancreaticoduodectomy with vascular reconstructionen_US
dc.typeConference_Paperen_US
dc.identifier.emailCheung, TT: cheung68@hku.hken_US
dc.identifier.emailPoon, RTP: poontp@hku.hken_US
dc.identifier.emailChan, ACY: acchan@hku.hken_US
dc.identifier.emailDai, WC: daiwc@hku.hken_US
dc.identifier.emailFan, ST: stfan@hku.hk-
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hk-
dc.identifier.authorityPoon, RTP=rp00446en_US
dc.identifier.authorityChan, ACY=rp00310en_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.identifier.hkuros237462en_US
dc.identifier.spageabstract no. 296-
dc.identifier.epageabstract no. 296-

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