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Conference Paper: Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells

TitleEffects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells
Authors
KeywordsMedical sciences
Issue Date2014
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
Citation
The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 34, abstract no. 52 How to Cite?
AbstractINTRODUCTION: Serotonin (5-hydrotrytamine, 5-HT) plays an important role in pulmonary functions. It is synthesised from tryptophan by aromatic 1-amino acid decarboxylase (AADC) and released at the sites, which binds to 5-HT receptors at the postsynaptic ends. Excess or turnover 5-HT will be recycled back into cells via 5-HT reuptake transporter (SERT), stored or subsequently metabolised by monoamine oxidase A (MAO-A) inside the cells. With the influence of smoking on serotoninergic neurons, we hypothesised that there may be a potential 5-HT analogue in cigarette smoke. We aimed to study the effect of 5-HT on interleukin (IL)–8 release and the effects of cigarette smoke on the metabolism of 5-HT in human bronchial epithelial …
Persistent Identifierhttp://hdl.handle.net/10722/204303
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorMak, JCWen_US
dc.contributor.authorLau, WKWen_US
dc.contributor.authorIp, MSMen_US
dc.date.accessioned2014-09-19T21:43:26Z-
dc.date.available2014-09-19T21:43:26Z-
dc.date.issued2014en_US
dc.identifier.citationThe 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 34, abstract no. 52en_US
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/204303-
dc.description.abstractINTRODUCTION: Serotonin (5-hydrotrytamine, 5-HT) plays an important role in pulmonary functions. It is synthesised from tryptophan by aromatic 1-amino acid decarboxylase (AADC) and released at the sites, which binds to 5-HT receptors at the postsynaptic ends. Excess or turnover 5-HT will be recycled back into cells via 5-HT reuptake transporter (SERT), stored or subsequently metabolised by monoamine oxidase A (MAO-A) inside the cells. With the influence of smoking on serotoninergic neurons, we hypothesised that there may be a potential 5-HT analogue in cigarette smoke. We aimed to study the effect of 5-HT on interleukin (IL)–8 release and the effects of cigarette smoke on the metabolism of 5-HT in human bronchial epithelial …-
dc.languageengen_US
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk-
dc.relation.ispartofHong Kong Medical Journalen_US
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectMedical sciences-
dc.titleEffects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cellsen_US
dc.typeConference_Paperen_US
dc.identifier.emailMak, JCW: judithmak@hku.hken_US
dc.identifier.emailLau, WKW: wayhku@hkucc.hku.hken_US
dc.identifier.emailIp, MSM: msmip@hku.hken_US
dc.identifier.authorityMak, JCW=rp00352en_US
dc.identifier.authorityIp, MSM=rp00347en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros240407en_US
dc.identifier.volume20en_US
dc.identifier.issuesuppl. 1en_US
dc.identifier.spage34en_US
dc.identifier.epage34en_US
dc.publisher.placeHong Kong-

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