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Conference Paper: Further evidence that the 3’Untranslated Region of the CHOP mRNA possesses mRNA destabilizing effect

TitleFurther evidence that the 3’Untranslated Region of the CHOP mRNA possesses mRNA destabilizing effect
Authors
Issue Date2014
Citation
The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 23, poster no. 22 How to Cite?
AbstractThe transcription regulatory factor known as Chop is commonly induced to express in stressed cells. In most cases, the expression of CHOP is associated with apoptosis. Although the regulation of CHOP expression at the transcriptional level has been studied to considerable details, the involvement of post-transcriptional mechanism such as mRNA stability has not been much addressed. We previously provided indirect evidence that the 3’UTR of CHOP mRNA had an mRNA destabilizing effect. The objective of this study was to provide more direct evidence to support this hypothesis. A reporter plasmid was constructed so as to express an EGFP mRNA that has its original ...
DescriptionPoster presentation - Theme 1: Cell biology
Persistent Identifierhttp://hdl.handle.net/10722/203852

 

DC FieldValueLanguage
dc.contributor.authorWong, PYen_US
dc.contributor.authorWong, NSen_US
dc.date.accessioned2014-09-19T16:42:19Z-
dc.date.available2014-09-19T16:42:19Z-
dc.date.issued2014en_US
dc.identifier.citationThe 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 23, poster no. 22en_US
dc.identifier.urihttp://hdl.handle.net/10722/203852-
dc.descriptionPoster presentation - Theme 1: Cell biology-
dc.description.abstractThe transcription regulatory factor known as Chop is commonly induced to express in stressed cells. In most cases, the expression of CHOP is associated with apoptosis. Although the regulation of CHOP expression at the transcriptional level has been studied to considerable details, the involvement of post-transcriptional mechanism such as mRNA stability has not been much addressed. We previously provided indirect evidence that the 3’UTR of CHOP mRNA had an mRNA destabilizing effect. The objective of this study was to provide more direct evidence to support this hypothesis. A reporter plasmid was constructed so as to express an EGFP mRNA that has its original ...-
dc.languageengen_US
dc.relation.ispartofHong Kong Inter-University Biochemistry Postgraduate Symposium 2014en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleFurther evidence that the 3’Untranslated Region of the CHOP mRNA possesses mRNA destabilizing effecten_US
dc.typeConference_Paperen_US
dc.identifier.emailWong, NS: nswong@hku.hken_US
dc.identifier.authorityWong, NS=rp00340en_US
dc.description.naturepostprint-
dc.identifier.hkuros240330en_US
dc.identifier.hkuros270511-
dc.identifier.spage23, poster no. 22-
dc.identifier.epage23, poster no. 22-

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