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Conference Paper: Gene expression noise in transcriptional negative auto-regulation in mammalian cell

TitleGene expression noise in transcriptional negative auto-regulation in mammalian cell
Authors
Issue Date2014
Citation
The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 20, poster no. 15 How to Cite?
AbstractNegative auto-regulation (N.A.R) is the simplest and most widely spread type of genetic network motif. Although previous work has demonstrated that N.A.R can reduce gene expression noise, the dynamic relationship between repression strength and its noise reduction effect has not been well documented in Mammalian cell. Here we construct N.A.R cascades using repressor tetR to suppress its own promoter, which contains different number of tetR binding site, in HEK 293 cell. To measure protein production ...
DescriptionPoster presentation - Theme 1: Cell biology
Persistent Identifierhttp://hdl.handle.net/10722/203850

 

DC FieldValueLanguage
dc.contributor.authorLiu, Len_US
dc.contributor.authorHuang, Jen_US
dc.date.accessioned2014-09-19T16:42:19Z-
dc.date.available2014-09-19T16:42:19Z-
dc.date.issued2014en_US
dc.identifier.citationThe 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 20, poster no. 15en_US
dc.identifier.urihttp://hdl.handle.net/10722/203850-
dc.descriptionPoster presentation - Theme 1: Cell biology-
dc.description.abstractNegative auto-regulation (N.A.R) is the simplest and most widely spread type of genetic network motif. Although previous work has demonstrated that N.A.R can reduce gene expression noise, the dynamic relationship between repression strength and its noise reduction effect has not been well documented in Mammalian cell. Here we construct N.A.R cascades using repressor tetR to suppress its own promoter, which contains different number of tetR binding site, in HEK 293 cell. To measure protein production ...-
dc.languageengen_US
dc.relation.ispartofHong Kong Inter-University Biochemistry Postgraduate Symposium 2014en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleGene expression noise in transcriptional negative auto-regulation in mammalian cellen_US
dc.typeConference_Paperen_US
dc.identifier.emailLiu, L: lzliu@hku.hken_US
dc.identifier.emailHuang, J: jdhuang@hku.hken_US
dc.identifier.authorityHuang, J=rp00451en_US
dc.description.naturepostprint-
dc.identifier.hkuros240327en_US
dc.identifier.hkuros270510-
dc.identifier.spage20, poster no. 15-
dc.identifier.epage20, poster no. 15-

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