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Conference Paper: Role of ATM signaling in PALB2-dependent DNA damage responses

TitleRole of ATM signaling in PALB2-dependent DNA damage responses
Authors
Guo, YFeng, WSy, MHHuen, MSY
Issue Date2014
Citation
The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 16, poster no. 8 How to Cite?
AbstractMutations of the PALB2 gene lead to a number of hereditary cancer-predisposing syndromes, including Fanconi anemia and hereditary breast and ovarian cancer syndrome. Originally identified as a core DNA repair factor, emerging evidence now implicates PALB2 in cell cycle checkpoint control, DNA replication, oxidative stress regulation and transcription, highlighting the multi-functionality of the tumor suppressor. Notably, mechanistically how its expanding repertoire of functions are orchestrated remains ...
DescriptionPoster presentation - Theme 1: Cell biology
Persistent Identifierhttp://hdl.handle.net/10722/203724

 

DC FieldValueLanguage
dc.contributor.authorGuo, Yen_US
dc.contributor.authorFeng, Wen_US
dc.contributor.authorSy, MHen_US
dc.contributor.authorHuen, MSYen_US
dc.date.accessioned2014-09-19T16:11:31Z-
dc.date.available2014-09-19T16:11:31Z-
dc.date.issued2014en_US
dc.identifier.citationThe 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 16, poster no. 8en_US
dc.identifier.urihttp://hdl.handle.net/10722/203724-
dc.descriptionPoster presentation - Theme 1: Cell biology-
dc.description.abstractMutations of the PALB2 gene lead to a number of hereditary cancer-predisposing syndromes, including Fanconi anemia and hereditary breast and ovarian cancer syndrome. Originally identified as a core DNA repair factor, emerging evidence now implicates PALB2 in cell cycle checkpoint control, DNA replication, oxidative stress regulation and transcription, highlighting the multi-functionality of the tumor suppressor. Notably, mechanistically how its expanding repertoire of functions are orchestrated remains ...-
dc.languageengen_US
dc.relation.ispartofHong Kong Inter-University Biochemistry Postgraduate Symposiumen_US
dc.titleRole of ATM signaling in PALB2-dependent DNA damage responsesen_US
dc.typeConference_Paperen_US
dc.identifier.emailGuo, Y: yyguo88@hku.hken_US
dc.identifier.emailFeng, W: fengwj83@hku.hken_US
dc.identifier.emailSy, MH: mhsy@hku.hken_US
dc.identifier.emailHuen, MSY: huen.michael@hku.hken_US
dc.identifier.authorityHuen, MSY=rp01336en_US
dc.description.naturepostprint-
dc.identifier.hkuros240317en_US
dc.identifier.spage16, poster no. 8-
dc.identifier.epage16, poster no. 8-

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