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Article: Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trial

TitleAcupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trial
Authors
Issue Date2013
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ecam/
Citation
Evidence-Based Complementary and Alternative Medicine, 2013, v. 2013, article no. 527303 How to Cite?
AbstractAcupuncture is an alternative therapy to induce ovulation in women with polycystic ovary syndrome (PCOS), but there is no study reporting the live birth rate following ovulation induction by acupuncture or its potential as an adjuvant treatment to clomiphene citrate (CC). We assess the efficacy of acupuncture with or without CC in achieving live births among 1000 PCOS women in Mainland China. This paper reports the methodology of an ongoing multicenter randomized controlled trial. The randomization scheme is coordinated through the central mechanism and stratified by the participating sites. Participants will be randomized into one of the four treatment arms: (A) true acupuncture and CC, (B) control acupuncture and CC, (C) true acupuncture and placebo CC, and (D) control acupuncture and placebo CC. To ensure the quality and integrity of the trial we have developed a unique multinational team of investigators and Data and Safety Monitoring Board. Up to the end of April 2013, 326 subjects were recruited. In conclusion, the success of this trial will allow us to evaluate the additional benefit of acupuncture beyond the first line medicine for fertility treatment in PCOS women in an unbiased manner.
Persistent Identifierhttp://hdl.handle.net/10722/203601
ISSN
2015 Impact Factor: 1.931
2015 SCImago Journal Rankings: 0.615
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKuang, Hen_US
dc.contributor.authorLi, Yen_US
dc.contributor.authorWu, Xen_US
dc.contributor.authorHou, Len_US
dc.contributor.authorWu, Ten_US
dc.contributor.authorLiu, Jen_US
dc.contributor.authorNg, EHYen_US
dc.date.accessioned2014-09-19T15:31:41Z-
dc.date.available2014-09-19T15:31:41Z-
dc.date.issued2013en_US
dc.identifier.citationEvidence-Based Complementary and Alternative Medicine, 2013, v. 2013, article no. 527303en_US
dc.identifier.issn1741-427X-
dc.identifier.urihttp://hdl.handle.net/10722/203601-
dc.description.abstractAcupuncture is an alternative therapy to induce ovulation in women with polycystic ovary syndrome (PCOS), but there is no study reporting the live birth rate following ovulation induction by acupuncture or its potential as an adjuvant treatment to clomiphene citrate (CC). We assess the efficacy of acupuncture with or without CC in achieving live births among 1000 PCOS women in Mainland China. This paper reports the methodology of an ongoing multicenter randomized controlled trial. The randomization scheme is coordinated through the central mechanism and stratified by the participating sites. Participants will be randomized into one of the four treatment arms: (A) true acupuncture and CC, (B) control acupuncture and CC, (C) true acupuncture and placebo CC, and (D) control acupuncture and placebo CC. To ensure the quality and integrity of the trial we have developed a unique multinational team of investigators and Data and Safety Monitoring Board. Up to the end of April 2013, 326 subjects were recruited. In conclusion, the success of this trial will allow us to evaluate the additional benefit of acupuncture beyond the first line medicine for fertility treatment in PCOS women in an unbiased manner.-
dc.languageengen_US
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ecam/-
dc.relation.ispartofEvidence-Based Complementary and Alternative Medicineen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleAcupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trialen_US
dc.typeArticleen_US
dc.identifier.emailNg, EHY: nghye@hku.hken_US
dc.identifier.authorityNg, EHY=rp00426en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2013/527303-
dc.identifier.pmid24023577-
dc.identifier.pmcidPMC3762180-
dc.identifier.hkuros238648en_US
dc.identifier.volume2013-
dc.identifier.isiWOS:000324061400001-
dc.publisher.placeUnited Kingdom-

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