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Article: Use of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Children

TitleUse of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Children
Authors
Issue Date2014
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0162-3257
Citation
Journal of Autism and Developmental Disorders, 2014, v. 44 n. 1, p. 9-18 How to Cite?
AbstractData from 1,261 Chinese Autistic Spectrum Disorder (ASD) patients were evaluated and categorized into dysmorphic (10.79 %) and non-dysmorphic groups (89.21 %) upon physical examination by the presence of dysmorphic features. Abnormal MRI/CT result, IQ scores and epilepsy were significantly associated with the dysmorphic group of ASD children. However, gender, EEG abnormality and family history and recurrence of ASD were not found to be significantly different between group statuses. It is suggested that results collected from the Chinese population generally resembles that found in the Caucasians with ethnical differences still present. Current study supports the result shown in Miles' study (Miles et al. in Am J Med Genet 135A:171-180, 2005), in which heterogeneity subtypes of autism of different genetic origins which could be distinguished by presence of dysmorphic features on the patients.
Persistent Identifierhttp://hdl.handle.net/10722/203280
ISSN
2015 Impact Factor: 3.493
2015 SCImago Journal Rankings: 1.877
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, VCNen_US
dc.contributor.authorFung, CKYen_US
dc.contributor.authorWong, PTYen_US
dc.date.accessioned2014-09-19T13:51:21Z-
dc.date.available2014-09-19T13:51:21Z-
dc.date.issued2014en_US
dc.identifier.citationJournal of Autism and Developmental Disorders, 2014, v. 44 n. 1, p. 9-18en_US
dc.identifier.issn0162-3257-
dc.identifier.urihttp://hdl.handle.net/10722/203280-
dc.description.abstractData from 1,261 Chinese Autistic Spectrum Disorder (ASD) patients were evaluated and categorized into dysmorphic (10.79 %) and non-dysmorphic groups (89.21 %) upon physical examination by the presence of dysmorphic features. Abnormal MRI/CT result, IQ scores and epilepsy were significantly associated with the dysmorphic group of ASD children. However, gender, EEG abnormality and family history and recurrence of ASD were not found to be significantly different between group statuses. It is suggested that results collected from the Chinese population generally resembles that found in the Caucasians with ethnical differences still present. Current study supports the result shown in Miles' study (Miles et al. in Am J Med Genet 135A:171-180, 2005), in which heterogeneity subtypes of autism of different genetic origins which could be distinguished by presence of dysmorphic features on the patients.-
dc.languageengen_US
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0162-3257-
dc.relation.ispartofJournal of Autism and Developmental Disordersen_US
dc.rightsThe original publication is available at www.springerlink.com-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleUse of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Childrenen_US
dc.typeArticleen_US
dc.identifier.emailWong, VCN: vcnwong@hku.hken_US
dc.identifier.emailWong, PTY: pollywongty@gmail.com-
dc.identifier.authorityWong, VCN=rp00334en_US
dc.description.naturepostprint-
dc.identifier.doi10.1007/s10803-013-1846-3en_US
dc.identifier.pmid23666520-
dc.identifier.hkuros240022en_US
dc.identifier.volume44en_US
dc.identifier.issue1en_US
dc.identifier.spage9en_US
dc.identifier.epage18en_US
dc.identifier.isiWOS:000329233000002-
dc.publisher.placeUnited States-

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