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Article: Clarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedside

TitleClarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedside
Authors
Issue Date2014
PublisherE-Century Publishing Corporation. The Journal's web site is located at http://www.ijcep.com
Citation
International Journal of Clinical and Experimental Pathology, 2014, v. 7 n. 4, p. 1293-1298 How to Cite?
AbstractAs a significant determinant of low back pain, intervertebral disc degeneration (IDD) has attracted more and more attention of both investigators and physicians. Disc herniation, termed as intervertebral disc displacement, is amongst the most prevalent spinal diseases closely linked with IDD. Due to the same origins and similar pathophysiology, the ambiguity regarding the similarity and difference of IDD and intervertebral disc displacement thus remains. The aim of this study was to clarify the nomenclature of IDD and disc herniation in terms of molecular etiology, pathophysiology, nature history and clinical outcomes. Collectively, IDD is a type of multifaceted, progressive spinal disease with or without clinical symptoms as back pain, characterized by extracellular matrix and the integrity of NP and AF lost, fissures formation. Disc herniation (termed as intervertebral disc displacement) is a type of spinal disease based on IDD or not, with local pain and/or sciatica due to mechanical compression and autoimmune cascades upon the corresponding nerve roots. Clarifying the nomenclature of intervertebral disc degeneration and displacement has important implications both for investigators and for physicians.
Persistent Identifierhttp://hdl.handle.net/10722/203247
ISSN
2015 Impact Factor: 1.581
2015 SCImago Journal Rankings: 0.617
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorWang, HQen_US
dc.contributor.authorSamartzis, Den_US
dc.date.accessioned2014-09-19T13:11:33Z-
dc.date.available2014-09-19T13:11:33Z-
dc.date.issued2014en_US
dc.identifier.citationInternational Journal of Clinical and Experimental Pathology, 2014, v. 7 n. 4, p. 1293-1298en_US
dc.identifier.issn1936-2625en_US
dc.identifier.urihttp://hdl.handle.net/10722/203247-
dc.description.abstractAs a significant determinant of low back pain, intervertebral disc degeneration (IDD) has attracted more and more attention of both investigators and physicians. Disc herniation, termed as intervertebral disc displacement, is amongst the most prevalent spinal diseases closely linked with IDD. Due to the same origins and similar pathophysiology, the ambiguity regarding the similarity and difference of IDD and intervertebral disc displacement thus remains. The aim of this study was to clarify the nomenclature of IDD and disc herniation in terms of molecular etiology, pathophysiology, nature history and clinical outcomes. Collectively, IDD is a type of multifaceted, progressive spinal disease with or without clinical symptoms as back pain, characterized by extracellular matrix and the integrity of NP and AF lost, fissures formation. Disc herniation (termed as intervertebral disc displacement) is a type of spinal disease based on IDD or not, with local pain and/or sciatica due to mechanical compression and autoimmune cascades upon the corresponding nerve roots. Clarifying the nomenclature of intervertebral disc degeneration and displacement has important implications both for investigators and for physicians.en_US
dc.languageengen_US
dc.publisherE-Century Publishing Corporation. The Journal's web site is located at http://www.ijcep.com-
dc.relation.ispartofInternational Journal of Clinical and Experimental Pathologyen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleClarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedsideen_US
dc.typeArticleen_US
dc.identifier.emailSamartzis, D: dspine@hku.hken_US
dc.identifier.authoritySamartzis, D=rp01430en_US
dc.description.naturepublished_or_final_version-
dc.identifier.pmid24817926-
dc.identifier.pmcidPMC4014210-
dc.identifier.hkuros238002en_US
dc.identifier.hkuros256017-
dc.identifier.volume7en_US
dc.identifier.issue4en_US
dc.identifier.spage1293en_US
dc.identifier.epage1298en_US
dc.publisher.placeUnited States-

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