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Article: Condition-specific measure was more responsive than generic measure in colorectal cancer: All but social domains

TitleCondition-specific measure was more responsive than generic measure in colorectal cancer: All but social domains
Authors
KeywordsSF-12
Anchor
Chinese
Colorectal cancer
FACT-C
Responsiveness
Issue Date2013
Citation
Journal of Clinical Epidemiology, 2013, v. 66, n. 5, p. 557-565 How to Cite?
AbstractObjective: To examine the responsiveness of generic and condition-specific instruments based on the anchor of self-reported level of global change in patients with colorectal cancer (CRC). Study Design and Setting: Three hundred thirty-three patients with CRC were surveyed at two assessments at baseline and follow-up at 6 months from September 2009 to July 2010 using the Short Form-12 Health Survey version 2 (SF-12v2) and Functional Assessment of Cancer Therapy-Colorectal (FACT-C) measures. The responsiveness of the two measures was evaluated using standardized effect size, standardized response mean, responsiveness statistic, and receiver operating characteristic (ROC) curve analysis. Results: In worsened group, internal responsiveness of detecting negative changes was satisfactory for most subscales of FACT-C and SF-12v2. The FACT-C subscales were significantly more responsive to positive changes detection than the SF-12v2 subscales in improved group. Physical well-being subscale, Trial Outcome Index (TOI), and total score of FACT-C were more externally responsive to ROC curve analysis. The FACT-C measure was generally more responsive to changes in health status compared with SF-12v2 measure. Conclusion: TOI and total score of FACT-C were the most responsive among subscales of condition-specific measure, which were more responsive than all generic subscales with the exception of social domain. Complementary use of condition-specific and generic instruments to evaluate the health-related quality of life of CRC patients is encouraged. © 2013 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/202202
ISSN
2015 Impact Factor: 4.703
2015 SCImago Journal Rankings: 2.559
ISI Accession Number ID
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DC FieldValueLanguage
dc.contributor.authorWong, Carlos K. H.-
dc.contributor.authorLam, Cindy Lo Kuen-
dc.contributor.authorLaw, Wai Lun-
dc.contributor.authorPoon, Jensen-
dc.contributor.authorKwong, Dora L W-
dc.contributor.authorTsang, Janice-
dc.contributor.authorWan, Yukfai-
dc.date.accessioned2014-08-22T02:57:48Z-
dc.date.available2014-08-22T02:57:48Z-
dc.date.issued2013-
dc.identifier.citationJournal of Clinical Epidemiology, 2013, v. 66, n. 5, p. 557-565-
dc.identifier.issn0895-4356-
dc.identifier.urihttp://hdl.handle.net/10722/202202-
dc.description.abstractObjective: To examine the responsiveness of generic and condition-specific instruments based on the anchor of self-reported level of global change in patients with colorectal cancer (CRC). Study Design and Setting: Three hundred thirty-three patients with CRC were surveyed at two assessments at baseline and follow-up at 6 months from September 2009 to July 2010 using the Short Form-12 Health Survey version 2 (SF-12v2) and Functional Assessment of Cancer Therapy-Colorectal (FACT-C) measures. The responsiveness of the two measures was evaluated using standardized effect size, standardized response mean, responsiveness statistic, and receiver operating characteristic (ROC) curve analysis. Results: In worsened group, internal responsiveness of detecting negative changes was satisfactory for most subscales of FACT-C and SF-12v2. The FACT-C subscales were significantly more responsive to positive changes detection than the SF-12v2 subscales in improved group. Physical well-being subscale, Trial Outcome Index (TOI), and total score of FACT-C were more externally responsive to ROC curve analysis. The FACT-C measure was generally more responsive to changes in health status compared with SF-12v2 measure. Conclusion: TOI and total score of FACT-C were the most responsive among subscales of condition-specific measure, which were more responsive than all generic subscales with the exception of social domain. Complementary use of condition-specific and generic instruments to evaluate the health-related quality of life of CRC patients is encouraged. © 2013 Elsevier Inc. All rights reserved.-
dc.languageeng-
dc.relation.ispartofJournal of Clinical Epidemiology-
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Journal of Clinical Epidemiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Clinical Epidemiology, [VOL 66, ISSUE 5, 2013] DOI 10.1016/j.jclinepi.2012.11.010-
dc.subjectSF-12-
dc.subjectAnchor-
dc.subjectChinese-
dc.subjectColorectal cancer-
dc.subjectFACT-C-
dc.subjectResponsiveness-
dc.titleCondition-specific measure was more responsive than generic measure in colorectal cancer: All but social domains-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jclinepi.2012.11.010-
dc.identifier.pmid23548135-
dc.identifier.scopuseid_2-s2.0-84875745423-
dc.identifier.hkuros213388-
dc.identifier.volume66-
dc.identifier.issue5-
dc.identifier.spage557-
dc.identifier.epage565-
dc.identifier.eissn1878-5921-
dc.identifier.isiWOS:000317557400014-
dc.relation.projectA Study on Health-related Quality of Life of patients with Colorectal Neoplasm and Cost-Effectiveness Analysis of Colorectal Cancer Screening in Hong Kong-

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