Excellent outcomes of severely steatotic grafts in liver transplantation

Abstract

Liver graft with macrovesicular steatosis >60% is considered unsuitable for deceased donor liver transplantation (DDLT) as previous study showed high risk for primary nonfunction (PNF) and graft loss.We report our outcomes in using severely steatotic grafts due to the shortage of deceased donors. Method We retrospectively analyzed patients’ outcomes after DDLT from 1991 to 2013. Macrovesicular steatosis>60% at post perfusion biopsy was defi ned as severe steatosis.Outcomes eg. postoperative complication/PNF and survival were compared to patients who received a graft without severe steatosis. Data was retrieved from a prospectively collected database. Results 374 patients underwent DDLT and 20 patients received severely steatotic graft and 354 patients had graft with steatosis<60%.Median degree of steatosis in severe steatosis group was85%(60-100%).Transplantation related characteristics were listed in .....