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Conference Paper: sPDZD2: a novel negative modulator of hedgehog signaling

TitlesPDZD2: a novel negative modulator of hedgehog signaling
Authors
Issue Date2014
Citation
The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 40, poster no. 51 How to Cite?
AbstractPDZD2 is a multi-PDZ domain-containing protein of unknown function in early development. It is proteolytically cleaved to generate its secreted form, sPDZD2. Human PDZD2 is mapped to chromosome 5p13.2, which co-localizes with the disease-associated gene in a family of Brachydactyly Type A1 (BDA1) patients, suggesting involvement of PDZD2 in limb development. Hedgehog (Hh) is an important morphogen that dictates tissue patterning during embryonic development and recent studies showed that mutations in Indian Hedgehog (IHH) resulted in ...
DescriptionPoster Presentation - Theme 3: Development & stem cells
Persistent Identifierhttp://hdl.handle.net/10722/201187

 

DC FieldValueLanguage
dc.contributor.authorTsui, MGen_US
dc.contributor.authorChan, Den_US
dc.contributor.authorCheah, Ken_US
dc.contributor.authorCheung, Men_US
dc.contributor.authorYao, KMen_US
dc.date.accessioned2014-08-21T07:16:32Z-
dc.date.available2014-08-21T07:16:32Z-
dc.date.issued2014en_US
dc.identifier.citationThe 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 40, poster no. 51en_US
dc.identifier.urihttp://hdl.handle.net/10722/201187-
dc.descriptionPoster Presentation - Theme 3: Development & stem cells-
dc.description.abstractPDZD2 is a multi-PDZ domain-containing protein of unknown function in early development. It is proteolytically cleaved to generate its secreted form, sPDZD2. Human PDZD2 is mapped to chromosome 5p13.2, which co-localizes with the disease-associated gene in a family of Brachydactyly Type A1 (BDA1) patients, suggesting involvement of PDZD2 in limb development. Hedgehog (Hh) is an important morphogen that dictates tissue patterning during embryonic development and recent studies showed that mutations in Indian Hedgehog (IHH) resulted in ...-
dc.languageengen_US
dc.relation.ispartofHong Kong Inter-University Biochemistry Postgraduate Symposiumen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titlesPDZD2: a novel negative modulator of hedgehog signalingen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, D: chand@hku.hken_US
dc.identifier.emailCheah, K: hrmbdkc@hku.hken_US
dc.identifier.emailCheung, M: mcheung9@hku.hken_US
dc.identifier.emailYao, KM: kmyao@hku.hken_US
dc.identifier.authorityChan, D=rp00540en_US
dc.identifier.authorityCheah, K=rp00342en_US
dc.identifier.authorityCheung, M=rp00245en_US
dc.identifier.authorityYao, KM=rp00344en_US
dc.description.naturepostprint-
dc.identifier.hkuros234999en_US
dc.identifier.hkuros240396-
dc.identifier.spage40, poster no. 51-
dc.identifier.epage40, poster no. 51-

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