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  Patent History
  • Application
    PC T/CN2013086954 2013-11-12
  • Publication
    WO 2014071892 2014-05-15
  Patent Family
Supplementary

granted patent: LAMIN A, AN ACTIVATOR OF LONGEVITY/ANTI-AGING SIRT1 PROTEIN

TitleLAMIN A, AN ACTIVATOR OF LONGEVITY/ANTI-AGING SIRT1 PROTEIN
Priority Date2012-11-12 US 12/1725252P
Inventors
Issue Date6-Aug-2014
Citation
WO Patent WO 2014071892. World Intellectual Property Organization (WIPO), PatentScope, 2014 How to Cite?
AbstractThe present invention provides methods of modulating the deacetylase activity of SIRT1 by modifying the binding affinity of lamin Ato SIRT1 via interaction modifying compound. The present invention also provides methods of screening SIRT1 modulating compounds based on the interaction between lamin A and SIRT1 protein and SIRT1-activating property of lamin A. The present invention further discloses uses of SIRT1 -activating compounds to treat patients suffering from metabolic and/or aging-related degenerative diseases, and uses of SIRT1 -inhibiting compounds to treat human malignancies.
Persistent Identifierhttp://hdl.handle.net/10722/200305

 

DC FieldValueLanguage
dc.date.accessioned2014-08-06T01:39:26Z-
dc.date.available2014-08-06T01:39:26Z-
dc.date.issued2014-08-06-
dc.identifier.citationWO Patent WO 2014071892. World Intellectual Property Organization (WIPO), PatentScope, 2014en_US
dc.identifier.urihttp://hdl.handle.net/10722/200305-
dc.description.abstractThe present invention provides methods of modulating the deacetylase activity of SIRT1 by modifying the binding affinity of lamin Ato SIRT1 via interaction modifying compound. The present invention also provides methods of screening SIRT1 modulating compounds based on the interaction between lamin A and SIRT1 protein and SIRT1-activating property of lamin A. The present invention further discloses uses of SIRT1 -activating compounds to treat patients suffering from metabolic and/or aging-related degenerative diseases, and uses of SIRT1 -inhibiting compounds to treat human malignancies.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleLAMIN A, AN ACTIVATOR OF LONGEVITY/ANTI-AGING SIRT1 PROTEINen_US
dc.typePatenten_US
dc.identifier.authorityZHOU, ZHONGJUN=rp00503en_US
dc.identifier.authorityLIU, BAOHUA=rp01485en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorZHOU, ZHONGJUNen_US
dc.contributor.inventorLIU, BAOHUAen_US
patents.identifier.applicationPC T/CN2013086954en_US
patents.description.assigneeUNIV HONG KONG [CN]en_US
patents.description.countryWorld Intellectual Property Organization (WIPO)en_US
patents.date.publication2014-05-15en_US
patents.date.application2013-11-12en_US
patents.date.priority2012-11-12 US 12/1725252Pen_US
patents.description.ccwoen_US
patents.identifier.publicationWO 2014071892en_US
patents.relation.familyUS 2014135271 (A1) 2014-05-15en_US
patents.description.kindA1en_US
patents.typePatent_granteden_US

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