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Conference Paper: An ex-vivo study of caries arrested with silver diamine fluoride

TitleAn ex-vivo study of caries arrested with silver diamine fluoride
Authors
KeywordsDentin
Fluoride
Silver and Teeth
Issue Date2014
PublisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
The 92nd General Session & Exhibition of the International Association for Dental Research (IADR), Cape Town, South Africa, 25-28 June 2014. In Journal of Dental Research, 2014, v. 93 n. Special issue B: abstract no. 613 How to Cite?
AbstractObjective: This ex vivostudy compared the physico-chemical structural differences between primary carious teeth in young children biannually treated with silver diamine fluoride (SDF) and carious teeth without such treatment. Method: Twelve carious primary upper central incisors were collected from 6-year-old children. Six teeth had arrested caries after 24-month biannual SDF applications and 6 had active caries when there was no topical fluoride treatment. The mineral density and crystal characteristics were assessed by micro-computed tomography (micro-CT), and transmission electron microscopy (TEM). Result: Micro-CT examination revealed a superficial opaque band approximately 150 µm in depth in the arrested cavitated dentinal lesion. This band was limited in the active carious lesion. Needle-shaped crystallites could be seen under TEM in the fine particles collected from the surface of the arrested dentinal lesion. Lattice spacing and intersection characteristics of hydroxyapatite could be identified at high magnification. The arc-shaped selected area electron diffraction (SAED) patterns suggested that the c-axes of the hydroxyapatite platelets had a preferential orientation. In contrast, crystallites could barely be recognized in the active dentinal lesion; only rounded crystallites were found at high magnification. The crystallites were generally smaller than those observed in the arrested dentinal lesion. SAED of these structures were devoid of arc-shaped patterns, suggesting a more random crystallite arrangement. Conclusion: A highly remineralised zone with well aligned hydroxyapatites was found on the arrested cavitated dentinal lesion of primary teeth which had received topical SDF applications.
DescriptionPoster Presentation
Session 97: Fluoride and Ca-based Products
Persistent Identifierhttp://hdl.handle.net/10722/199328
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714

 

DC FieldValueLanguage
dc.contributor.authorMei, Len_US
dc.contributor.authorLo, ECMen_US
dc.date.accessioned2014-07-22T01:13:39Z-
dc.date.available2014-07-22T01:13:39Z-
dc.date.issued2014en_US
dc.identifier.citationThe 92nd General Session & Exhibition of the International Association for Dental Research (IADR), Cape Town, South Africa, 25-28 June 2014. In Journal of Dental Research, 2014, v. 93 n. Special issue B: abstract no. 613en_US
dc.identifier.issn0022-0345en_US
dc.identifier.urihttp://hdl.handle.net/10722/199328-
dc.descriptionPoster Presentation-
dc.descriptionSession 97: Fluoride and Ca-based Products-
dc.description.abstractObjective: This ex vivostudy compared the physico-chemical structural differences between primary carious teeth in young children biannually treated with silver diamine fluoride (SDF) and carious teeth without such treatment. Method: Twelve carious primary upper central incisors were collected from 6-year-old children. Six teeth had arrested caries after 24-month biannual SDF applications and 6 had active caries when there was no topical fluoride treatment. The mineral density and crystal characteristics were assessed by micro-computed tomography (micro-CT), and transmission electron microscopy (TEM). Result: Micro-CT examination revealed a superficial opaque band approximately 150 µm in depth in the arrested cavitated dentinal lesion. This band was limited in the active carious lesion. Needle-shaped crystallites could be seen under TEM in the fine particles collected from the surface of the arrested dentinal lesion. Lattice spacing and intersection characteristics of hydroxyapatite could be identified at high magnification. The arc-shaped selected area electron diffraction (SAED) patterns suggested that the c-axes of the hydroxyapatite platelets had a preferential orientation. In contrast, crystallites could barely be recognized in the active dentinal lesion; only rounded crystallites were found at high magnification. The crystallites were generally smaller than those observed in the arrested dentinal lesion. SAED of these structures were devoid of arc-shaped patterns, suggesting a more random crystallite arrangement. Conclusion: A highly remineralised zone with well aligned hydroxyapatites was found on the arrested cavitated dentinal lesion of primary teeth which had received topical SDF applications.-
dc.languageengen_US
dc.publisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925en_US
dc.relation.ispartofJournal of Dental Researchen_US
dc.rightsJournal of Dental Research. Copyright © Sage Publications, Inc.en_US
dc.subjectDentin-
dc.subjectFluoride-
dc.subjectSilver and Teeth-
dc.titleAn ex-vivo study of caries arrested with silver diamine fluorideen_US
dc.typeConference_Paperen_US
dc.identifier.emailMei, L: mei1123@hku.hken_US
dc.identifier.emailLo, ECM: edward-lo@hku.hken_US
dc.identifier.authorityMei, L=rp01840en_US
dc.identifier.authorityLo, ECM=rp00015en_US
dc.identifier.hkuros231064en_US
dc.identifier.volume93en_US
dc.identifier.issueSpecial issue B: abstract no. 613en_US
dc.publisher.placeUnited Statesen_US

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