File Download
  Links for fulltext
     (May Require Subscription)
  • Find via Find It@HKUL
Supplementary

Article: Transmission of avian influenza A(H7N9) virus from father to child: a report of limited person-to-person transmission, Guangzhou, China, January 2014

TitleTransmission of avian influenza A(H7N9) virus from father to child: a report of limited person-to-person transmission, Guangzhou, China, January 2014
Authors
Issue Date2014
PublisherEuropean Centre for Disease Prevention and Control. The Journal's web site is located at http://www.eurosurveillance.org/Public/AboutUs/AboutUs.aspx
Citation
Eurosurveillance, 2014, v. 19 n. 25, p. article no. 3 How to Cite?
AbstractWe investigated a possible person-to-person transmission within a family cluster of two confirmed influenza A(H7N9) patients in Guangzhou, China. The index case, a man in his late twenties, worked in a wet market that was confirmed to be contaminated by the influenza A(H7N9) virus. He developed a consistent fever and severe pneumonia after 4 January 2014. In contrast, the second case, his five-year-old child, who only developed a mild disease 10 days after disease onset of the index case, did not have any contact with poultry and birds but had unprotected and very close contact with the index case. The sequences of the haemagglutinin (HA) genes of the virus stains isolated from the two cases were 100% identical. These findings strongly suggest that the second case might have acquired the infection via transmission of the virus from the sick father. Fortunately, all 40 close contacts, including the other four family members who also had unprotected and very close contact with the cases, did not acquire influenza A(H7N9) virus infection, indicating that the person-to-person transmissibility of the virus remained limited. Our finding underlines the importance of carefully, thoroughly and punctually following- up close contacts of influenza A(H7N9) cases to allow detection of any secondary cases, as these may constitute an early warning signal of the virus’s increasing ability to transmit from person-to-person.
Persistent Identifierhttp://hdl.handle.net/10722/199188
ISSN
2015 SCImago Journal Rankings: 2.112

 

DC FieldValueLanguage
dc.contributor.authorXiao, XCen_US
dc.contributor.authorLi, KBen_US
dc.contributor.authorChen, ZQen_US
dc.contributor.authorDi, Ben_US
dc.contributor.authorYang, ZCen_US
dc.contributor.authorYuan, Jen_US
dc.contributor.authorLuo, HBen_US
dc.contributor.authorYe, SLen_US
dc.contributor.authorLiu, Hen_US
dc.contributor.authorLu, JYen_US
dc.contributor.authorNie, Zen_US
dc.contributor.authorTang, XPen_US
dc.contributor.authorWang, Men_US
dc.contributor.authorZheng, BJen_US
dc.date.accessioned2014-07-22T01:06:19Z-
dc.date.available2014-07-22T01:06:19Z-
dc.date.issued2014en_US
dc.identifier.citationEurosurveillance, 2014, v. 19 n. 25, p. article no. 3en_US
dc.identifier.issn1025-496X-
dc.identifier.urihttp://hdl.handle.net/10722/199188-
dc.description.abstractWe investigated a possible person-to-person transmission within a family cluster of two confirmed influenza A(H7N9) patients in Guangzhou, China. The index case, a man in his late twenties, worked in a wet market that was confirmed to be contaminated by the influenza A(H7N9) virus. He developed a consistent fever and severe pneumonia after 4 January 2014. In contrast, the second case, his five-year-old child, who only developed a mild disease 10 days after disease onset of the index case, did not have any contact with poultry and birds but had unprotected and very close contact with the index case. The sequences of the haemagglutinin (HA) genes of the virus stains isolated from the two cases were 100% identical. These findings strongly suggest that the second case might have acquired the infection via transmission of the virus from the sick father. Fortunately, all 40 close contacts, including the other four family members who also had unprotected and very close contact with the cases, did not acquire influenza A(H7N9) virus infection, indicating that the person-to-person transmissibility of the virus remained limited. Our finding underlines the importance of carefully, thoroughly and punctually following- up close contacts of influenza A(H7N9) cases to allow detection of any secondary cases, as these may constitute an early warning signal of the virus’s increasing ability to transmit from person-to-person.en_US
dc.languageengen_US
dc.publisherEuropean Centre for Disease Prevention and Control. The Journal's web site is located at http://www.eurosurveillance.org/Public/AboutUs/AboutUs.aspx-
dc.relation.ispartofEurosurveillanceen_US
dc.titleTransmission of avian influenza A(H7N9) virus from father to child: a report of limited person-to-person transmission, Guangzhou, China, January 2014en_US
dc.typeArticleen_US
dc.identifier.emailZheng, BJ: bzheng@hkucc.hku.hken_US
dc.identifier.authorityZheng, B=rp00353en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros231145en_US
dc.identifier.volume19en_US
dc.identifier.issue25en_US
dc.identifier.spagearticle no. 3en_US
dc.identifier.epagearticle no. 3en_US
dc.publisher.placeSweden-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats