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Article: Flies and fish: Birds of a feather

TitleFlies and fish: Birds of a feather
Authors
Issue Date2003
Citation
Journal of Neuroendocrinology, 2003, v. 15 n. 4, p. 344-349 How to Cite?
AbstractThe identification of specific clock-containing structures has been a major endeavour of the circadian field for many years. This has lead to the identification of many key components of the circadian system, including the suprachiasmatic nucleus in mammals, and the eyes and pineal glands in lower vertebrates. However, the idea that these structures represent the only clocks in animals has been challenged by the discovery of peripheral pacemakers in most organs and tissues, and even a number of cell lines. In Drosophila, and vertebrates such as the zebrafish, these peripheral clocks appear to be highly autonomous, being set directly by the environmental light/dark cycle. However, a hierarchy of clocks may still exist in mammals. In this review, we examine some of the current views regarding peripheral clocks, their organization and how they are entrained.
Persistent Identifierhttp://hdl.handle.net/10722/197944
ISSN
2015 Impact Factor: 3.172
2015 SCImago Journal Rankings: 1.541

 

DC FieldValueLanguage
dc.contributor.authorTamai, TK-
dc.contributor.authorVardhanabhuti, V-
dc.contributor.authorArthur, S-
dc.contributor.authorFoulkes, NS-
dc.contributor.authorWhitmore, D-
dc.date.accessioned2014-06-16T03:40:02Z-
dc.date.available2014-06-16T03:40:02Z-
dc.date.issued2003-
dc.identifier.citationJournal of Neuroendocrinology, 2003, v. 15 n. 4, p. 344-349-
dc.identifier.issn0953-8194-
dc.identifier.urihttp://hdl.handle.net/10722/197944-
dc.description.abstractThe identification of specific clock-containing structures has been a major endeavour of the circadian field for many years. This has lead to the identification of many key components of the circadian system, including the suprachiasmatic nucleus in mammals, and the eyes and pineal glands in lower vertebrates. However, the idea that these structures represent the only clocks in animals has been challenged by the discovery of peripheral pacemakers in most organs and tissues, and even a number of cell lines. In Drosophila, and vertebrates such as the zebrafish, these peripheral clocks appear to be highly autonomous, being set directly by the environmental light/dark cycle. However, a hierarchy of clocks may still exist in mammals. In this review, we examine some of the current views regarding peripheral clocks, their organization and how they are entrained.-
dc.languageeng-
dc.relation.ispartofJournal of Neuroendocrinology-
dc.titleFlies and fish: Birds of a feather-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1365-2826.2003.00974.x-
dc.identifier.pmid12622832-
dc.identifier.scopuseid_2-s2.0-0037379996-
dc.identifier.volume15-
dc.identifier.issue4-
dc.identifier.spage344-
dc.identifier.epage349-

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