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Conference Paper: Feasibility study of low-dose CT colonography using model-based iterative reconstruction: preliminary findings in 20 patients

TitleFeasibility study of low-dose CT colonography using model-based iterative reconstruction: preliminary findings in 20 patients
Authors
Issue Date2013
PublisherSpringerOpen.
Citation
The 2013 European Congress of Radiology, Vienna, Austria, 7–11 March 2013. In Insights into Imaging, 2013, v. 4 n. 1 suppl., p. S330 How to Cite?
AbstractPurpose: To compare image quality on computed tomographic (CT) images acquired at standard dose (SD) and low dose (LD) using adaptive statistical iterative reconstruction (ASIR) and model-based iterative reconstruction (MBIR) techniques. Methods and Materials: 20 patients were prospectively recruited for the study with informed consent. They underwent standard dose (SD) and low-dose (LD) CT colonography. Low-dose parameters were based on our phantom study with using vendor-specific automatic tube current modulation known as noise index. Both sets of scans were reconstructed with ASIR and MBIR. Objective and subjective image qualities were assessed as well as diagnostic accuracies for significant lesions (e.g. polyps, cancer, etc). Effective doses for each scans were recorded. Results: Objective image analysis supports significant noise reduction and superior contrast-to-noise ratio with low-dose scans using MBIR technique (p < 0.05) despite being acquired at lower doses. Subjective image parameters were equivalent for LD MBIR and SD ASIR for both colonic and extra-colonic findings. Diagnostic accuracies for polyp detection and other significant lesions were comparable. Dose recorded were substantially lower for MBIR (range 45-75% reduction compared with ASIR) with mean average being 4.2 mSv in our population group. Conclusion: MBIR shows superior reduction in noise whilst maintaining image quality and most importantly substantial dose reduction can be achieved. More patients are being recruited to substantiate diagnostic accuracies data with full results to be presented at the ECR 2013.
Persistent Identifierhttp://hdl.handle.net/10722/197931
ISSN
2015 SCImago Journal Rankings: 1.004

 

DC FieldValueLanguage
dc.contributor.authorVardhanabhuti, V-
dc.contributor.authorRoobottom, CA-
dc.date.accessioned2014-06-13T08:19:12Z-
dc.date.available2014-06-13T08:19:12Z-
dc.date.issued2013-
dc.identifier.citationThe 2013 European Congress of Radiology, Vienna, Austria, 7–11 March 2013. In Insights into Imaging, 2013, v. 4 n. 1 suppl., p. S330-
dc.identifier.issn1869-4101-
dc.identifier.urihttp://hdl.handle.net/10722/197931-
dc.description.abstractPurpose: To compare image quality on computed tomographic (CT) images acquired at standard dose (SD) and low dose (LD) using adaptive statistical iterative reconstruction (ASIR) and model-based iterative reconstruction (MBIR) techniques. Methods and Materials: 20 patients were prospectively recruited for the study with informed consent. They underwent standard dose (SD) and low-dose (LD) CT colonography. Low-dose parameters were based on our phantom study with using vendor-specific automatic tube current modulation known as noise index. Both sets of scans were reconstructed with ASIR and MBIR. Objective and subjective image qualities were assessed as well as diagnostic accuracies for significant lesions (e.g. polyps, cancer, etc). Effective doses for each scans were recorded. Results: Objective image analysis supports significant noise reduction and superior contrast-to-noise ratio with low-dose scans using MBIR technique (p < 0.05) despite being acquired at lower doses. Subjective image parameters were equivalent for LD MBIR and SD ASIR for both colonic and extra-colonic findings. Diagnostic accuracies for polyp detection and other significant lesions were comparable. Dose recorded were substantially lower for MBIR (range 45-75% reduction compared with ASIR) with mean average being 4.2 mSv in our population group. Conclusion: MBIR shows superior reduction in noise whilst maintaining image quality and most importantly substantial dose reduction can be achieved. More patients are being recruited to substantiate diagnostic accuracies data with full results to be presented at the ECR 2013.-
dc.languageeng-
dc.publisherSpringerOpen.-
dc.relation.ispartofInsights into Imaging-
dc.titleFeasibility study of low-dose CT colonography using model-based iterative reconstruction: preliminary findings in 20 patientsen_US
dc.typeConference_Paperen_US
dc.identifier.emailVardhanabhuti, V: varv@hku.hk-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s13244-013-0228-x-
dc.identifier.volume4-
dc.identifier.issue1 suppl.-
dc.identifier.spageS330-
dc.identifier.epageS330-
dc.publisher.placeGermany-

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