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Conference Paper: Prediction of suicidal behavior in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow-up study

TitlePrediction of suicidal behavior in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow-up study
Authors
Issue Date2014
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
The 4th Biennial Schizophrenia International Research Conference, Florence, Italy, 5-9 April 2014. In Schizophrenia Research, 2014, v. 153 suppl. 1, p. S190, poster no. M3 How to Cite?
AbstractBACKGROUND: Suicide behaviours are common in the early stage of psychotic disorders. The present study aimed to examine the rate and predictors of suicidal behaviours in the initial 3 years of treatment for patients presenting with first-episode psychosis to a territory-wide specialized early intervention program, namely EASY (Early Assessment Service for Young people with psychosis) in Hong Kong. METHODS: Seven hundred patients aged 15-25 years presenting with first episode psychosis (based on ICD-10 criteria) to EASY program between July 2001 and August 2003 were included in the study. Of the initial cohort, 546 completed the 3-year follow-up and thus constituted the final study sample. Demographics, past history of suicidal attempts, substance abuse, baseline and follow-up clinical and functioning variables were collected via systematic medical record review based on standardized protocol. Suicidal behaviour was defined as either attempted or committed suicide. A series of univariate logistic regression analyses were performed to examine the relationship of suicidal behaviour (yes/no in 3-year follow-up) with potential predictor variables, followed by multivariate regression model to determine independent predictors of suicidal behaviours. RESULTS: There were no significant differences between completers and non-completers in socio-demographics, past suicidal attempt, baseline clinical and functional measures with the exception that completers were significantly more likely to have schizophrenia diagnosis. By the end of 3-year follow-up, 11.2% (n=61) of patients exhibited suicidal behaviour over the study period, including 1.3% (n=7) committing suicide. Univariate analyses revealed that hospitalization at intake (OR=0.45, p<0.05), past history of substance abuse (OR=0.43, p<0.05), pre-treatment suicidal attempt (OR=0.38, p<0.01), and baseline social functioning (OR=0.97, p<0.01) were identified as the risk factors for suicidal behaviours. Multivariate regression demonstrated that only pre-treatment suicidal attempt, past history of substance abuse and baseline functioning independently predicted the occurrence of suicidal behaviours during 3-year follow-up period (Nagelkerke R2 = 0.064, chi-square= 21.8, p<0.0001). DISCUSSION: In a large representative cohort of Chinese young patients with first-episode psychosis, we found that 3-year prevalence rate for suicidal behaviours and suicide was 11.2% and 1.3%, respectively. Pre-treatment suicidal attempt, past history of substance abuse and baseline functioning were shown to independently predict suicidal behaviours in the initial 3 years of treatment for first-episode psychosis in EASY program..
DescriptionThis journal suppl. entitled: Abstracts of the 4th Biennial Schizophrenia International Research Conference
Poster no. M3
Persistent Identifierhttp://hdl.handle.net/10722/197705
ISSN
2015 Impact Factor: 4.453
2015 SCImago Journal Rankings: 2.304

 

DC FieldValueLanguage
dc.contributor.authorChen, SMen_US
dc.contributor.authorChang, WCen_US
dc.contributor.authorHui, CLMen_US
dc.contributor.authorChan, KWen_US
dc.contributor.authorLee, HMEen_US
dc.contributor.authorChen, EYHen_US
dc.date.accessioned2014-05-29T08:43:29Z-
dc.date.available2014-05-29T08:43:29Z-
dc.date.issued2014en_US
dc.identifier.citationThe 4th Biennial Schizophrenia International Research Conference, Florence, Italy, 5-9 April 2014. In Schizophrenia Research, 2014, v. 153 suppl. 1, p. S190, poster no. M3en_US
dc.identifier.issn0920-9964-
dc.identifier.urihttp://hdl.handle.net/10722/197705-
dc.descriptionThis journal suppl. entitled: Abstracts of the 4th Biennial Schizophrenia International Research Conference-
dc.descriptionPoster no. M3-
dc.description.abstractBACKGROUND: Suicide behaviours are common in the early stage of psychotic disorders. The present study aimed to examine the rate and predictors of suicidal behaviours in the initial 3 years of treatment for patients presenting with first-episode psychosis to a territory-wide specialized early intervention program, namely EASY (Early Assessment Service for Young people with psychosis) in Hong Kong. METHODS: Seven hundred patients aged 15-25 years presenting with first episode psychosis (based on ICD-10 criteria) to EASY program between July 2001 and August 2003 were included in the study. Of the initial cohort, 546 completed the 3-year follow-up and thus constituted the final study sample. Demographics, past history of suicidal attempts, substance abuse, baseline and follow-up clinical and functioning variables were collected via systematic medical record review based on standardized protocol. Suicidal behaviour was defined as either attempted or committed suicide. A series of univariate logistic regression analyses were performed to examine the relationship of suicidal behaviour (yes/no in 3-year follow-up) with potential predictor variables, followed by multivariate regression model to determine independent predictors of suicidal behaviours. RESULTS: There were no significant differences between completers and non-completers in socio-demographics, past suicidal attempt, baseline clinical and functional measures with the exception that completers were significantly more likely to have schizophrenia diagnosis. By the end of 3-year follow-up, 11.2% (n=61) of patients exhibited suicidal behaviour over the study period, including 1.3% (n=7) committing suicide. Univariate analyses revealed that hospitalization at intake (OR=0.45, p<0.05), past history of substance abuse (OR=0.43, p<0.05), pre-treatment suicidal attempt (OR=0.38, p<0.01), and baseline social functioning (OR=0.97, p<0.01) were identified as the risk factors for suicidal behaviours. Multivariate regression demonstrated that only pre-treatment suicidal attempt, past history of substance abuse and baseline functioning independently predicted the occurrence of suicidal behaviours during 3-year follow-up period (Nagelkerke R2 = 0.064, chi-square= 21.8, p<0.0001). DISCUSSION: In a large representative cohort of Chinese young patients with first-episode psychosis, we found that 3-year prevalence rate for suicidal behaviours and suicide was 11.2% and 1.3%, respectively. Pre-treatment suicidal attempt, past history of substance abuse and baseline functioning were shown to independently predict suicidal behaviours in the initial 3 years of treatment for first-episode psychosis in EASY program..-
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres-
dc.relation.ispartofSchizophrenia Researchen_US
dc.titlePrediction of suicidal behavior in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow-up studyen_US
dc.typeConference_Paperen_US
dc.identifier.emailChang, WC: changwc@hku.hken_US
dc.identifier.emailHui, CLM: christyh@hkucc.hku.hken_US
dc.identifier.emailChan, KW: kwsherry@hku.hken_US
dc.identifier.emailLee, HME: edwinlhm@hku.hken_US
dc.identifier.emailChen, EYH: eyhchen@hku.hken_US
dc.identifier.authorityChang, WC=rp01465en_US
dc.identifier.authorityChan, KW=rp00539en_US
dc.identifier.authorityLee, HME=rp01575en_US
dc.identifier.authorityChen, EYH=rp00392en_US
dc.identifier.doi10.1016/S0920-9964(14)70553-5-
dc.identifier.hkuros229005en_US
dc.identifier.hkuros249085-
dc.identifier.volume153en_US
dc.identifier.issuesuppl. 1en_US
dc.identifier.spageS190, poster no. M3en_US
dc.identifier.epageS190, poster no. M3en_US
dc.publisher.placeNetherlands-

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