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Article: Carotid atherosclerosis and the risk factors in early postmenopausal Chinese women

TitleCarotid atherosclerosis and the risk factors in early postmenopausal Chinese women
Authors
Issue Date2009
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/maturitas
Citation
Maturitas, 2009, v. 63 n. 3, p. 233-239 How to Cite?
AbstractOBJECTIVES: To describe the distribution of intima-media thickness (IMT) and the prevalence of plaque by carotid segments, walls and sides, and to examine their associated risk factors in asymptomatic, early postmenopausal Chinese women in Hong Kong. METHODS: Between 2002 and 2004, the study recruited 518 postmenopausal women aged 50-64 years. They were examined by B-mode ultrasound to measure the IMT and the prevalence of plaque at the near and far walls of common carotid (CCA), bifurcation (bulb), and internal carotid (ICA) of both the left and right carotid arteries. Blood pressures, obesity indices, lipids and glucose levels, sociodemographic, medical and lifestyle factors were also obtained. RESULTS: The mean IMT was 0.76+/-0.12 mm (range: 0.53-1.33 mm). IMT was significantly thicker on the far wall than on the near wall and differed among segments (being thickest at the bulb and the narrowest at the ICA). 21.8% had at least one plaque in the carotid artery with most of the plaque found at the bulb area. Systolic blood pressure had statistically significant relationship with IMT that were fairly homogeneous among different segments. Lipids were associated with the CCA and bulb IMT, but not the ICA IMT. Diabetes predicted only CCA IMT. Older age, higher waist-hip-ratio and low-density lipoprotein cholesterol were significant predictors of plaques at all sites combined. CONCLUSIONS: We described the distribution of IMT and the prevalence of plaque in asymptomatic, early postmenopausal Chinese women. Associations of risk factors with IMT of different arterial segments were also observed.
Persistent Identifierhttp://hdl.handle.net/10722/197265
ISSN
2015 Impact Factor: 3.12
2015 SCImago Journal Rankings: 1.107
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYu, RHYen_US
dc.contributor.authorHo, SCen_US
dc.contributor.authorHo, SSYen_US
dc.contributor.authorChan, SSGen_US
dc.contributor.authorWoo, JLFen_US
dc.contributor.authorAhuja, ATen_US
dc.date.accessioned2014-05-23T02:32:03Z-
dc.date.available2014-05-23T02:32:03Z-
dc.date.issued2009en_US
dc.identifier.citationMaturitas, 2009, v. 63 n. 3, p. 233-239en_US
dc.identifier.issn0378-5122-
dc.identifier.urihttp://hdl.handle.net/10722/197265-
dc.description.abstractOBJECTIVES: To describe the distribution of intima-media thickness (IMT) and the prevalence of plaque by carotid segments, walls and sides, and to examine their associated risk factors in asymptomatic, early postmenopausal Chinese women in Hong Kong. METHODS: Between 2002 and 2004, the study recruited 518 postmenopausal women aged 50-64 years. They were examined by B-mode ultrasound to measure the IMT and the prevalence of plaque at the near and far walls of common carotid (CCA), bifurcation (bulb), and internal carotid (ICA) of both the left and right carotid arteries. Blood pressures, obesity indices, lipids and glucose levels, sociodemographic, medical and lifestyle factors were also obtained. RESULTS: The mean IMT was 0.76+/-0.12 mm (range: 0.53-1.33 mm). IMT was significantly thicker on the far wall than on the near wall and differed among segments (being thickest at the bulb and the narrowest at the ICA). 21.8% had at least one plaque in the carotid artery with most of the plaque found at the bulb area. Systolic blood pressure had statistically significant relationship with IMT that were fairly homogeneous among different segments. Lipids were associated with the CCA and bulb IMT, but not the ICA IMT. Diabetes predicted only CCA IMT. Older age, higher waist-hip-ratio and low-density lipoprotein cholesterol were significant predictors of plaques at all sites combined. CONCLUSIONS: We described the distribution of IMT and the prevalence of plaque in asymptomatic, early postmenopausal Chinese women. Associations of risk factors with IMT of different arterial segments were also observed.-
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/maturitas-
dc.relation.ispartofMaturitasen_US
dc.subject.meshCarotid Arteries - pathology - ultrasonography-
dc.subject.meshCarotid Artery Diseases - ethnology - etiology - ultrasonography-
dc.subject.meshHypertension - complications-
dc.subject.meshLipids - blood-
dc.subject.meshPostmenopause-
dc.titleCarotid atherosclerosis and the risk factors in early postmenopausal Chinese womenen_US
dc.typeArticleen_US
dc.identifier.emailYu, RHY: rubyyu@hkucc.hku.hken_US
dc.identifier.doi10.1016/j.maturitas.2009.03.022-
dc.identifier.pmid19443144-
dc.identifier.hkuros160079en_US
dc.identifier.volume63en_US
dc.identifier.issue3-
dc.identifier.spage233en_US
dc.identifier.epage239en_US
dc.identifier.isiWOS:000268643500012-
dc.publisher.placeIreland-

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