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Article: Central synapse and neuromuscular junction: Same players, different roles

TitleCentral synapse and neuromuscular junction: Same players, different roles
Authors
Issue Date2003
Citation
Trends in Genetics, 2003, v. 19 n. 7, p. 395-402 How to Cite?
AbstractThe central synapse in the brain and the neuromuscular synapse between motor neuron and muscle fiber are structurally and functionally distinct. Recent studies, however, have identified the localization and potential functions of signaling molecules common to both types of synapse. Strikingly, many of these molecules also have important roles in axon guidance and neurite outgrowth. Among these molecules are the cyclin-dependent kinase Cdk5, agrin, the agrin receptor MuSK, ephrin and the ephrin receptor Eph. Here we summarize the recent findings illustrating the diverse functions of these multi-talented molecules.
Persistent Identifierhttp://hdl.handle.net/10722/196674
ISSN
2015 Impact Factor: 9.858
2015 SCImago Journal Rankings: 7.849
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLai, K-O-
dc.contributor.authorIp, NY-
dc.date.accessioned2014-04-24T02:10:32Z-
dc.date.available2014-04-24T02:10:32Z-
dc.date.issued2003-
dc.identifier.citationTrends in Genetics, 2003, v. 19 n. 7, p. 395-402-
dc.identifier.issn0168-9525-
dc.identifier.urihttp://hdl.handle.net/10722/196674-
dc.description.abstractThe central synapse in the brain and the neuromuscular synapse between motor neuron and muscle fiber are structurally and functionally distinct. Recent studies, however, have identified the localization and potential functions of signaling molecules common to both types of synapse. Strikingly, many of these molecules also have important roles in axon guidance and neurite outgrowth. Among these molecules are the cyclin-dependent kinase Cdk5, agrin, the agrin receptor MuSK, ephrin and the ephrin receptor Eph. Here we summarize the recent findings illustrating the diverse functions of these multi-talented molecules.-
dc.languageeng-
dc.relation.ispartofTrends in Genetics-
dc.titleCentral synapse and neuromuscular junction: Same players, different roles-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0168-9525(03)00147-1-
dc.identifier.pmid12850445-
dc.identifier.scopuseid_2-s2.0-0038015606-
dc.identifier.volume19-
dc.identifier.issue7-
dc.identifier.spage395-
dc.identifier.epage402-
dc.identifier.isiWOS:000184538400011-

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