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Article: Double-pulsed diffusional kurtosis imaging

TitleDouble-pulsed diffusional kurtosis imaging
Authors
Issue Date2014
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291099-1492
Citation
NMR in Biomedicine, 2014, v. 27 n. 4, p. 363-370 How to Cite?
AbstractDiffusional kurtosis imaging (DKI) is extended to double-pulsed-field-gradient (d-PFG) diffusion MRI sequences. This gives a practical approach for acquiring and analyzing d-PFG data. In particular, the leading d-PFG effects, beyond what conventional single-pulsed field gradient (s-PFG) provides, are interpreted in terms of the kurtosis for a diffusion displacement probability density function (dPDF) in a six-dimensional (6D) space. The 6D diffusional kurtosis encodes the unique information provided by d-PFG sequences up to second order in the b-value. This observation leads to a compact expression for the signal magnitude, and it suggests novel data acquisition and analysis methods. Double-pulsed DKI (DP-DKI) is demonstrated for in vivo mouse brain with d-PFG data obtained at 7 T
Persistent Identifierhttp://hdl.handle.net/10722/196274
ISSN
2015 SCImago Journal Rankings: 1.533
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJensen, JHen_US
dc.contributor.authorHui, SKen_US
dc.contributor.authorHelpern, JAen_US
dc.date.accessioned2014-04-01T08:44:42Z-
dc.date.available2014-04-01T08:44:42Z-
dc.date.issued2014en_US
dc.identifier.citationNMR in Biomedicine, 2014, v. 27 n. 4, p. 363-370en_US
dc.identifier.issn1099-1492-
dc.identifier.urihttp://hdl.handle.net/10722/196274-
dc.description.abstractDiffusional kurtosis imaging (DKI) is extended to double-pulsed-field-gradient (d-PFG) diffusion MRI sequences. This gives a practical approach for acquiring and analyzing d-PFG data. In particular, the leading d-PFG effects, beyond what conventional single-pulsed field gradient (s-PFG) provides, are interpreted in terms of the kurtosis for a diffusion displacement probability density function (dPDF) in a six-dimensional (6D) space. The 6D diffusional kurtosis encodes the unique information provided by d-PFG sequences up to second order in the b-value. This observation leads to a compact expression for the signal magnitude, and it suggests novel data acquisition and analysis methods. Double-pulsed DKI (DP-DKI) is demonstrated for in vivo mouse brain with d-PFG data obtained at 7 Ten_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291099-1492-
dc.relation.ispartofNMR in Biomedicineen_US
dc.rightsNMR in Biomedicine. Copyright © John Wiley & Sons Ltd.-
dc.titleDouble-pulsed diffusional kurtosis imagingen_US
dc.typeArticleen_US
dc.identifier.emailHui, SK: edshui@hku.hken_US
dc.identifier.authorityHui, SK=rp01832en_US
dc.identifier.doi10.1002/nbm.3094-
dc.identifier.pmid24677661-
dc.identifier.hkuros228427en_US
dc.identifier.volume27en_US
dc.identifier.issue4-
dc.identifier.spage363en_US
dc.identifier.epage370en_US
dc.identifier.isiWOS:000332988500001-
dc.publisher.placeUnited Kingdom-

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