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    PC T/CN2013071155 2013-01-30
  • Publication
    WO 2013113279 2013-08-08
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granted patent: DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE

TitleDIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE
Priority Date2012-01-30 US 12/1592122P
Inventors
Issue Date2013
Citation
WO Patent WO 2013113279. World Intellectual Property Organization (WIPO), PatentScope, 2013 How to Cite?
AbstractProvided herein are improved fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening peroxynitrite. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. Also provided herein are fluorogenic compounds for selectively staining peroxynitrite in the mitochondria of living cells. Provided also herein are methods that can be used to measure, directly or indirectly, the presence and/or amount of peroxynitrite in chemical samples and biological samples such as cells and tissues in living organisms. Also provided are high- throughput screening methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite in chemical and biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/195813
References

 

DC FieldValueLanguage
dc.date.accessioned2014-03-12T09:15:01Z-
dc.date.available2014-03-12T09:15:01Z-
dc.date.issued2013-
dc.identifier.citationWO Patent WO 2013113279. World Intellectual Property Organization (WIPO), PatentScope, 2013en_US
dc.identifier.urihttp://hdl.handle.net/10722/195813-
dc.description.abstractProvided herein are improved fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening peroxynitrite. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. Also provided herein are fluorogenic compounds for selectively staining peroxynitrite in the mitochondria of living cells. Provided also herein are methods that can be used to measure, directly or indirectly, the presence and/or amount of peroxynitrite in chemical samples and biological samples such as cells and tissues in living organisms. Also provided are high- throughput screening methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite in chemical and biological samples.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documentsen_US
dc.titleDIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITEen_US
dc.typePatenten_US
dc.identifier.authorityYANG, DAN=rp00825en_US
dc.identifier.authoritySHEN, JIANGANG=rp00487en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorYANG, DANen_US
dc.contributor.inventorPENG, TAOen_US
dc.contributor.inventorSHEN, JIANGANGen_US
dc.contributor.inventorCHEN, XINGMIAOen_US
patents.identifier.applicationPC T/CN2013071155en_US
patents.description.assigneeUNIV HONG KONG [CN]en_US
patents.description.countryWorld Intellectual Property Organization (WIPO)en_US
patents.date.publication2013-08-08en_US
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patents.identifier.hkutechidChm-2011-00382-2-
patents.date.application2013-01-30en_US
patents.date.priority2012-01-30 US 12/1592122Pen_US
patents.description.ccwoen_US
patents.identifier.publicationWO 2013113279en_US
patents.relation.familyUS 2013196362 (A1) 2013-08-01en_US
patents.description.kindA1en_US
patents.typePatent_granteden_US

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