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Conference Paper: Diffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissue

TitleDiffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissue
Authors
Issue Date2012
Citation
ISMRM 20th Annual Meeting, 2012 How to Cite?
AbstractThe diagnostic value of ADC obtained from DWI is often dwarfed by its pseudonormalization during subacute stroke. It is therefore necessary to find an alternative that is more sensitive and specific to the underlying structural changes along the course of ischemic infarction. One potential technique is diffusion kurtosis imaging (DKI) which measures non-Gaussianity of water diffusion. The current study showed that MK is a sensitive biomarker for ischemic injury, especially subacute stroke where MD and T2W pseudonormalize as a result of vasogenic edema. DKI could potentially complement conventional DWI for improving stroke diagnosis, particularly during the subacute phase.
Persistent Identifierhttp://hdl.handle.net/10722/195271

 

DC FieldValueLanguage
dc.contributor.authorHui, SKen_US
dc.contributor.authorLee, CYen_US
dc.contributor.authorDebbins, JPen_US
dc.contributor.authorDuong, TQen_US
dc.contributor.authorHelpern, JAen_US
dc.date.accessioned2014-02-26T02:07:49Z-
dc.date.available2014-02-26T02:07:49Z-
dc.date.issued2012en_US
dc.identifier.citationISMRM 20th Annual Meeting, 2012en_US
dc.identifier.urihttp://hdl.handle.net/10722/195271-
dc.description.abstractThe diagnostic value of ADC obtained from DWI is often dwarfed by its pseudonormalization during subacute stroke. It is therefore necessary to find an alternative that is more sensitive and specific to the underlying structural changes along the course of ischemic infarction. One potential technique is diffusion kurtosis imaging (DKI) which measures non-Gaussianity of water diffusion. The current study showed that MK is a sensitive biomarker for ischemic injury, especially subacute stroke where MD and T2W pseudonormalize as a result of vasogenic edema. DKI could potentially complement conventional DWI for improving stroke diagnosis, particularly during the subacute phase.en_US
dc.languageengen_US
dc.relation.ispartofISMRM 20th Annual Meetingen_US
dc.titleDiffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissueen_US
dc.typeConference_Paperen_US
dc.identifier.emailHui, SK: edshui@hku.hken_US
dc.identifier.authorityHui, SK=rp01832en_US

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