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Conference Paper: Investigation of the chronic effect of streptozotocin-induced diabetes on cerebrovascular reactivity and BOLD fmri response to electrical forepaw stimulation

TitleInvestigation of the chronic effect of streptozotocin-induced diabetes on cerebrovascular reactivity and BOLD fmri response to electrical forepaw stimulation
Authors
Issue Date2012
Citation
ISMRM 20th Annual Meeting, 2012 How to Cite?
AbstractSomatosensory responses to nociceptive and non-nociceptive stimuli were altered in the peripheral nervous system (PNS) of diabetic rats (first month after STZ injection) and patients. However, more evidences suggested that the central nervous system (CNS) was also involved. For instance, the evoked potential amplitude in S1 was reduced at 8 weeks of diabetes. Furthermore, a resting state fMRI, which examines neuronal connectivity, study showed impairment of the attention network to external stimuli in diabetic patientm. The goal of the current study was therefore to examine the longitudinal and chronic effect of diabetes on CNS using fMRI and CO2 challenge.
Persistent Identifierhttp://hdl.handle.net/10722/195263

 

DC FieldValueLanguage
dc.contributor.authorHui, SKen_US
dc.contributor.authorHuang, Sen_US
dc.contributor.authorShih, YYen_US
dc.contributor.authorDuong, TQen_US
dc.date.accessioned2014-02-26T02:07:46Z-
dc.date.available2014-02-26T02:07:46Z-
dc.date.issued2012en_US
dc.identifier.citationISMRM 20th Annual Meeting, 2012en_US
dc.identifier.urihttp://hdl.handle.net/10722/195263-
dc.description.abstractSomatosensory responses to nociceptive and non-nociceptive stimuli were altered in the peripheral nervous system (PNS) of diabetic rats (first month after STZ injection) and patients. However, more evidences suggested that the central nervous system (CNS) was also involved. For instance, the evoked potential amplitude in S1 was reduced at 8 weeks of diabetes. Furthermore, a resting state fMRI, which examines neuronal connectivity, study showed impairment of the attention network to external stimuli in diabetic patientm. The goal of the current study was therefore to examine the longitudinal and chronic effect of diabetes on CNS using fMRI and CO2 challenge.en_US
dc.languageengen_US
dc.relation.ispartofISMRM 20th Annual Meetingen_US
dc.titleInvestigation of the chronic effect of streptozotocin-induced diabetes on cerebrovascular reactivity and BOLD fmri response to electrical forepaw stimulationen_US
dc.typeConference_Paperen_US
dc.identifier.emailHui, SK: edshui@hku.hken_US
dc.identifier.authorityHui, SK=rp01832en_US

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