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Article: The new role of SAGE in gene discovery

TitleThe new role of SAGE in gene discovery
Authors
Issue Date2003
Citation
Trends in Biotechnology, 2003, v. 21 n. 2, p. 55-57 How to Cite?
AbstractThe sequencing of the human genome has led to in silico predictions of far fewer genes than anticipated. Recent studies using serial analysis of gene expression have cast doubt on this finding. One study predicts the presence of many unidentified low abundance transcripts, whereas two others have mapped unique tags to previously unpredicted exons. Genome and transcriptome complexity is thus greater than predicted and many of the missing genes are probably expressed in low copy numbers or only in early embryonic tissues.
Persistent Identifierhttp://hdl.handle.net/10722/195163
ISSN
2015 Impact Factor: 12.065
2015 SCImago Journal Rankings: 4.076
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBoheler, KR-
dc.contributor.authorStern, MD-
dc.date.accessioned2014-02-25T01:40:15Z-
dc.date.available2014-02-25T01:40:15Z-
dc.date.issued2003-
dc.identifier.citationTrends in Biotechnology, 2003, v. 21 n. 2, p. 55-57-
dc.identifier.issn0167-7799-
dc.identifier.urihttp://hdl.handle.net/10722/195163-
dc.description.abstractThe sequencing of the human genome has led to in silico predictions of far fewer genes than anticipated. Recent studies using serial analysis of gene expression have cast doubt on this finding. One study predicts the presence of many unidentified low abundance transcripts, whereas two others have mapped unique tags to previously unpredicted exons. Genome and transcriptome complexity is thus greater than predicted and many of the missing genes are probably expressed in low copy numbers or only in early embryonic tissues.-
dc.languageeng-
dc.relation.ispartofTrends in Biotechnology-
dc.titleThe new role of SAGE in gene discovery-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0167-7799(02)00031-8-
dc.identifier.pmid12573851-
dc.identifier.scopuseid_2-s2.0-0037309660-
dc.identifier.volume21-
dc.identifier.issue2-
dc.identifier.spage55-
dc.identifier.epage57-
dc.identifier.isiWOS:000181154900002-

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