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Article: The incidental findings of age-related macular degeneration during diabetic retinopathy screening

TitleThe incidental findings of age-related macular degeneration during diabetic retinopathy screening
Authors
Issue Date2014
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm
Citation
Graefe's Archive for Clinical and Experimental Ophthalmology, 2014, v. 252 n. 5, p. 723-729 How to Cite?
AbstractBackground: The purpose of this study was to determine the reliability of detecting age-related macular degeneration (AMD) during screening for diabetic retinopathy (DR). Methods: This prospective study included 2,003 subjects with diabetes mellitus who underwent photographic screening for DR. The reliability of detecting AMD lesions was tested by interobserver and intraobserver agreement, and the sensitivity and specificity of diagnosing AMD at different grades of severity were tested using the consensus grading of a group as the reference standard. Results: DR affected 24.7 % of the subjects. The age-standardized prevalence of early AMD was 17.9 %, and late AMD was 0.1 %. The interobserver and intraobserver agreement for grading AMD was substantial (k = 0.72 and 0.71 respectively, p < 0.001). It was equally good in those with different severities of DR. There was also no difference in sensitivity and specificity of detecting AMD in those with different levels of DR (sensitivity 62-68 % and specificity 97-98 %). Conclusion: Intermediate- and high-risk AMD that warrant treatment with zinc and anti-oxidant supplements could be reliably detected during screening for diabetic retinopathy. © 2013 Springer-Verlag Berlin Heidelberg.
Persistent Identifierhttp://hdl.handle.net/10722/195153
ISSN
2015 Impact Factor: 1.991
2015 SCImago Journal Rankings: 1.217
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorGangwani, R-
dc.contributor.authorLai, WW-
dc.contributor.authorSum, R-
dc.contributor.authorMcGhee, SM-
dc.contributor.authorChan, CWS-
dc.contributor.authorHedley, AJ-
dc.contributor.authorWong, D-
dc.date.accessioned2014-02-25T01:40:14Z-
dc.date.available2014-02-25T01:40:14Z-
dc.date.issued2014-
dc.identifier.citationGraefe's Archive for Clinical and Experimental Ophthalmology, 2014, v. 252 n. 5, p. 723-729-
dc.identifier.issn0721-832X-
dc.identifier.urihttp://hdl.handle.net/10722/195153-
dc.description.abstractBackground: The purpose of this study was to determine the reliability of detecting age-related macular degeneration (AMD) during screening for diabetic retinopathy (DR). Methods: This prospective study included 2,003 subjects with diabetes mellitus who underwent photographic screening for DR. The reliability of detecting AMD lesions was tested by interobserver and intraobserver agreement, and the sensitivity and specificity of diagnosing AMD at different grades of severity were tested using the consensus grading of a group as the reference standard. Results: DR affected 24.7 % of the subjects. The age-standardized prevalence of early AMD was 17.9 %, and late AMD was 0.1 %. The interobserver and intraobserver agreement for grading AMD was substantial (k = 0.72 and 0.71 respectively, p < 0.001). It was equally good in those with different severities of DR. There was also no difference in sensitivity and specificity of detecting AMD in those with different levels of DR (sensitivity 62-68 % and specificity 97-98 %). Conclusion: Intermediate- and high-risk AMD that warrant treatment with zinc and anti-oxidant supplements could be reliably detected during screening for diabetic retinopathy. © 2013 Springer-Verlag Berlin Heidelberg.-
dc.languageeng-
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm-
dc.relation.ispartofGraefe's Archive for Clinical and Experimental Ophthalmology-
dc.titleThe incidental findings of age-related macular degeneration during diabetic retinopathy screening-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00417-013-2530-1-
dc.identifier.pmid24281784-
dc.identifier.scopuseid_2-s2.0-84902285555-
dc.identifier.hkuros234663-
dc.identifier.spage723-
dc.identifier.epage729-
dc.identifier.isiWOS:000335660000003-

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