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Book Chapter: Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats

TitleExogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats
Authors
Issue Date1989
PublisherSpringer
Citation
Exogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats. In Meyer, EM, Simpkins, JW, and Yamamoto, J (Eds.), Novel Approaches to the Treatment of Alzheimer’s Disease, v. 36, p. 103-115. US: Springer, 1989 How to Cite?
AbstractNerve growth factor (NGF) is physiologically critical for the survival and normal development of sympathetic and spinal sensory neurons, and for their maintenance in the adult (1,2). NGF has been found to have a similar role in the mammalian central nervous system (CNS) (3). NGF was first implicated in CNS function when Schwab et al. (4) found specific retrograde transport of exogenous NGF from cerebral and hippocampal cortices to neuronal cell bodies in the rat basal forebrain. NGF is now known to be present and produced in the CNS, and is in largest amount in the cortex and hippocampus, the target tissues for neurons in the basal forebrain (3).
Persistent Identifierhttp://hdl.handle.net/10722/194887
ISBN
ISSN

 

DC FieldValueLanguage
dc.contributor.authorWilliams, LP-
dc.contributor.authorJodelis, KS-
dc.contributor.authorDonale, MR-
dc.contributor.authorYip, HKF-
dc.date.accessioned2014-02-17T06:27:59Z-
dc.date.available2014-02-17T06:27:59Z-
dc.date.issued1989-
dc.identifier.citationExogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged rats. In Meyer, EM, Simpkins, JW, and Yamamoto, J (Eds.), Novel Approaches to the Treatment of Alzheimer’s Disease, v. 36, p. 103-115. US: Springer, 1989-
dc.identifier.isbn978-1-4684-5729-2-
dc.identifier.issn0099-6246-
dc.identifier.urihttp://hdl.handle.net/10722/194887-
dc.description.abstractNerve growth factor (NGF) is physiologically critical for the survival and normal development of sympathetic and spinal sensory neurons, and for their maintenance in the adult (1,2). NGF has been found to have a similar role in the mammalian central nervous system (CNS) (3). NGF was first implicated in CNS function when Schwab et al. (4) found specific retrograde transport of exogenous NGF from cerebral and hippocampal cortices to neuronal cell bodies in the rat basal forebrain. NGF is now known to be present and produced in the CNS, and is in largest amount in the cortex and hippocampus, the target tissues for neurons in the basal forebrain (3).-
dc.languageeng-
dc.publisherSpringer-
dc.relation.ispartofNovel Approaches to the Treatment of Alzheimer’s Disease-
dc.titleExogenous nerve growth factor stimulates choline acetyltransferase activity in basal forebrain of axotomized and aged ratsen_US
dc.typeBook_Chapteren_US
dc.identifier.emailYip, HKF: hkfyip@hku.hk, hkfyip@hkusua.hku.hk-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/978-1-4684-5727-8_10-
dc.identifier.volume36-
dc.identifier.spage103-
dc.identifier.epage115-
dc.publisher.placeUS-

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