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Article: Long Term Survival Analysis of Hepatectomy for Neuroendocrine Tumour Liver Metastases

TitleLong Term Survival Analysis of Hepatectomy for Neuroendocrine Tumour Liver Metastases
Authors
Issue Date2014
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.tswj.com/
Citation
The Scientific World Journal, 2014, v. 2014, p. article no. 524045 How to Cite?
AbstractBackground. Liver is the commonest site for metastasis in patients with neuroendocrine tumour (NET). A vast majority of treatment strategies including liver directed nonsurgical therapy, liver directed surgical therapy, and nonliver directed therapy have been proposed. In this study we aim to investigate the outcome of liver resection in neuroendocrine tumour liver metastases (NELM). Method. 293 patients had hepatectomy for liver metastasis in our hospital between June 1996 and December 2010. Twelve patients were diagnosed to have NET in their final pathology and their data were reviewed. Results. The median ages of the patients were 48.5 years (range 20-71 years). Eight of the patients received major hepatectomy. Four patients received minor hepatectomy. The median operation time was 418 minutes (range 195-660 minutes). The median tumor size was 8.75 cm (range 0.9-21 cm). There was no hospital mortality. The overall one-year and three-year survivals were 91.7% and 55.6%. The one-year and three-year disease-free survivals were 33.3% and 16.7%. Conclusion. Hepatectomy is an effective and safe treatment for NELM. Reasonable outcome on long term overall survival and disease-free survival can be achieved in this group of patients with a low morbidity rate. © 2014 Tan To Cheung et al.
Persistent Identifierhttp://hdl.handle.net/10722/193878
ISSN
2013 Impact Factor: 1.219
2015 SCImago Journal Rankings: 0.315
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorCheung, TTen_US
dc.contributor.authorChok, KSHen_US
dc.contributor.authorChan, ACYen_US
dc.contributor.authorTsang, SHYen_US
dc.contributor.authorDai, WCen_US
dc.contributor.authorLang, HHBen_US
dc.contributor.authorYau, TCCen_US
dc.contributor.authorChan, SCen_US
dc.contributor.authorPoon, RTPen_US
dc.contributor.authorFan, STen_US
dc.contributor.authorLo, CMen_US
dc.date.accessioned2014-01-28T06:30:45Z-
dc.date.available2014-01-28T06:30:45Z-
dc.date.issued2014en_US
dc.identifier.citationThe Scientific World Journal, 2014, v. 2014, p. article no. 524045en_US
dc.identifier.issn1537-744X-
dc.identifier.urihttp://hdl.handle.net/10722/193878-
dc.description.abstractBackground. Liver is the commonest site for metastasis in patients with neuroendocrine tumour (NET). A vast majority of treatment strategies including liver directed nonsurgical therapy, liver directed surgical therapy, and nonliver directed therapy have been proposed. In this study we aim to investigate the outcome of liver resection in neuroendocrine tumour liver metastases (NELM). Method. 293 patients had hepatectomy for liver metastasis in our hospital between June 1996 and December 2010. Twelve patients were diagnosed to have NET in their final pathology and their data were reviewed. Results. The median ages of the patients were 48.5 years (range 20-71 years). Eight of the patients received major hepatectomy. Four patients received minor hepatectomy. The median operation time was 418 minutes (range 195-660 minutes). The median tumor size was 8.75 cm (range 0.9-21 cm). There was no hospital mortality. The overall one-year and three-year survivals were 91.7% and 55.6%. The one-year and three-year disease-free survivals were 33.3% and 16.7%. Conclusion. Hepatectomy is an effective and safe treatment for NELM. Reasonable outcome on long term overall survival and disease-free survival can be achieved in this group of patients with a low morbidity rate. © 2014 Tan To Cheung et al.-
dc.languageengen_US
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.tswj.com/-
dc.relation.ispartofThe Scientific World Journalen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleLong Term Survival Analysis of Hepatectomy for Neuroendocrine Tumour Liver Metastasesen_US
dc.typeArticleen_US
dc.identifier.emailCheung, TT: cheung68@hku.hken_US
dc.identifier.emailChok, KSH: chok6275@hku.hken_US
dc.identifier.emailChan, ACY: acchan@hku.hken_US
dc.identifier.emailDai, WC: daiwc@hku.hken_US
dc.identifier.emailLang, HHB: Blang@hku.hken_US
dc.identifier.emailYau, TCC: tyaucc@hku.hken_US
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hken_US
dc.identifier.emailPoon, RTP: poontp@hku.hken_US
dc.identifier.emailFan, ST: stfan@hku.hken_US
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_US
dc.identifier.authorityChan, ACY=rp00310en_US
dc.identifier.authorityLang, HHB=rp01828en_US
dc.identifier.authorityYau, TCC=rp01466en_US
dc.identifier.authorityChan, SC=rp01568en_US
dc.identifier.authorityPoon, RTP=rp00446en_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.identifier.authorityLo, CM=rp00412en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2014/524045-
dc.identifier.pmid24526905-
dc.identifier.pmcidPMC3913525-
dc.identifier.scopuseid_2-s2.0-84893855060-
dc.identifier.hkuros227562en_US
dc.identifier.volume2014en_US
dc.identifier.spagearticle no. 524045-
dc.identifier.epagearticle no. 524045-
dc.identifier.isiWOS:000330505600001-
dc.publisher.placeUnited States-

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