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Article: Microbiota in the oral subgingival biofilm is associated with obesity in adolescence

TitleMicrobiota in the oral subgingival biofilm is associated with obesity in adolescence
Authors
Issue Date2012
Citation
Obesity, 2012, v. 20 n. 1, p. 157-164 How to Cite?
AbstractTo test the hypothesis whether microbiota in oral biofilm is linked with obesity in adolescents we designed this cross-sectional study. Obese adolescents (n = 29) with a mean age of 14.7 years and normal weight subjects (n = 58) matched by age and gender were examined with respect to visible plaque index (VPI%) and gingival inflammation (bleeding on probing (BOP%)). Stimulated saliva was collected. They answered a questionnaire concerning medical history, medication, oral hygiene habits, smoking habits, and sociodemographic background. Microbiological samples taken from the gingival crevice was analyzed by checkerboard DNA-DNA hybridization technique. The sum of bacterial cells in subgingival biofilm was significantly associated with obesity (P < 0.001). The link between sum of bacterial cells and obesity was not confounded by any of the studied variables (chronic disease, medication, VPI%, BOP%, flow rate of whole saliva, or meal frequency). Totally 23 bacterial species were present in approximately threefold higher amounts, on average, in obese subjects compared with normal weight controls. Of the Proteobacteria phylum, Campylobacter rectus and Neisseria mucosa were present in sixfold higher amounts among obese subjects. The association between obesity and sum of bacterial cells in oral subgingival biofilm indicates a possible link between oral microbiota and obesity in adolescents. © 2011 The Obesity Society.
Persistent Identifierhttp://hdl.handle.net/10722/192705
ISSN
2015 Impact Factor: 3.614
2015 SCImago Journal Rankings: 2.016
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZeigler, CCen_US
dc.contributor.authorPersson, GRen_US
dc.contributor.authorWondimu, Ben_US
dc.contributor.authorMarcus, Cen_US
dc.contributor.authorSobko, Ten_US
dc.contributor.authorModéer, Ten_US
dc.date.accessioned2013-11-20T04:56:13Z-
dc.date.available2013-11-20T04:56:13Z-
dc.date.issued2012en_US
dc.identifier.citationObesity, 2012, v. 20 n. 1, p. 157-164en_US
dc.identifier.issn1930-7381en_US
dc.identifier.urihttp://hdl.handle.net/10722/192705-
dc.description.abstractTo test the hypothesis whether microbiota in oral biofilm is linked with obesity in adolescents we designed this cross-sectional study. Obese adolescents (n = 29) with a mean age of 14.7 years and normal weight subjects (n = 58) matched by age and gender were examined with respect to visible plaque index (VPI%) and gingival inflammation (bleeding on probing (BOP%)). Stimulated saliva was collected. They answered a questionnaire concerning medical history, medication, oral hygiene habits, smoking habits, and sociodemographic background. Microbiological samples taken from the gingival crevice was analyzed by checkerboard DNA-DNA hybridization technique. The sum of bacterial cells in subgingival biofilm was significantly associated with obesity (P < 0.001). The link between sum of bacterial cells and obesity was not confounded by any of the studied variables (chronic disease, medication, VPI%, BOP%, flow rate of whole saliva, or meal frequency). Totally 23 bacterial species were present in approximately threefold higher amounts, on average, in obese subjects compared with normal weight controls. Of the Proteobacteria phylum, Campylobacter rectus and Neisseria mucosa were present in sixfold higher amounts among obese subjects. The association between obesity and sum of bacterial cells in oral subgingival biofilm indicates a possible link between oral microbiota and obesity in adolescents. © 2011 The Obesity Society.en_US
dc.languageengen_US
dc.relation.ispartofObesityen_US
dc.titleMicrobiota in the oral subgingival biofilm is associated with obesity in adolescenceen_US
dc.typeArticleen_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1038/oby.2011.305en_US
dc.identifier.pmid21996660-
dc.identifier.scopuseid_2-s2.0-84655164378en_US
dc.identifier.volume20en_US
dc.identifier.issue1en_US
dc.identifier.spage157en_US
dc.identifier.epage164en_US
dc.identifier.isiWOS:000298401400018-

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