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Article: Cognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adults

TitleCognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adults
Authors
Issue Date2013
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=IPG
Citation
International Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association, 2013, v. 25 n. 7, p. 1125-1134 How to Cite?
AbstractBACKGROUND: This study evaluates which cognitive measure is best for predicting incident dementia in a population-based random sample of Chinese older adults without dementia over a five-year period. METHODS: A total of 787 community-dwelling Chinese older adults without dementia in Hong Kong were assessed at baseline (T0), at two years (T1), and at five years (T2). RESULTS: The annual conversion rate to dementia was 1.6% and 6.3% for baseline normal participants and baseline mild cognitive impairment (MCI) participants, respectively. The Cantonese version of Mini-mental State Examination (CMMSE) scores declined significantly over time. In participants who progressed to dementia, Category Verbal Fluency Test (CVFT) scores dropped significantly from T0 to T1. A 1-SD drop of either CMMSE or CVFT in two years predicted dementia at five years with 91.5% sensitivity and 62.0% specificity. A stable CMMSE and CVFT at two years predicted a 91% chance of not progressing to clinical dementia at five years. CONCLUSION: In this community sample of Chinese older adults, a decline in cognitive screening tests in short term (two years) offered useful information in predicting dementia conversion over a longer period.
Persistent Identifierhttp://hdl.handle.net/10722/189377
ISSN
2015 Impact Factor: 2.22
2015 SCImago Journal Rankings: 1.068
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, CHYen_US
dc.contributor.authorLeung, GTYen_US
dc.contributor.authorFung, AWTen_US
dc.contributor.authorChan, WCen_US
dc.contributor.authorLam, LCWen_US
dc.date.accessioned2013-09-17T14:38:06Z-
dc.date.available2013-09-17T14:38:06Z-
dc.date.issued2013en_US
dc.identifier.citationInternational Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association, 2013, v. 25 n. 7, p. 1125-1134en_US
dc.identifier.issn1041-6102-
dc.identifier.urihttp://hdl.handle.net/10722/189377-
dc.description.abstractBACKGROUND: This study evaluates which cognitive measure is best for predicting incident dementia in a population-based random sample of Chinese older adults without dementia over a five-year period. METHODS: A total of 787 community-dwelling Chinese older adults without dementia in Hong Kong were assessed at baseline (T0), at two years (T1), and at five years (T2). RESULTS: The annual conversion rate to dementia was 1.6% and 6.3% for baseline normal participants and baseline mild cognitive impairment (MCI) participants, respectively. The Cantonese version of Mini-mental State Examination (CMMSE) scores declined significantly over time. In participants who progressed to dementia, Category Verbal Fluency Test (CVFT) scores dropped significantly from T0 to T1. A 1-SD drop of either CMMSE or CVFT in two years predicted dementia at five years with 91.5% sensitivity and 62.0% specificity. A stable CMMSE and CVFT at two years predicted a 91% chance of not progressing to clinical dementia at five years. CONCLUSION: In this community sample of Chinese older adults, a decline in cognitive screening tests in short term (two years) offered useful information in predicting dementia conversion over a longer period.-
dc.languageengen_US
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=IPG-
dc.relation.ispartofInternational Psychogeriatrics: the official journal of the Interntional Psychogeriatric Associationen_US
dc.rightsInternational Psychogeriatrics: the official journal of the Interntional Psychogeriatric Association. Copyright © Cambridge University Press.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshAsian Continental Ancestry Group - psychology-
dc.subject.meshDementia - diagnosis - psychology-
dc.subject.meshGeriatric Assessment - methods - statistics and numerical data-
dc.subject.meshMental Status Schedule-
dc.subject.meshMild Cognitive Impairment - diagnosis-
dc.titleCognitive predictors for five-year conversion to dementia in community-dwelling Chinese older adultsen_US
dc.typeArticleen_US
dc.identifier.emailChan, WC: waicchan@hku.hken_US
dc.identifier.authorityChan, WC=rp01687en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1017/S1041610213000161-
dc.identifier.pmid23544873-
dc.identifier.hkuros223357en_US
dc.identifier.hkuros232518-
dc.identifier.volume25en_US
dc.identifier.issue7-
dc.identifier.spage1125en_US
dc.identifier.epage1134en_US
dc.identifier.isiWOS:000321262200010-
dc.publisher.placeUnited Kingdom-

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