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Article: The effect of chemotherapy and radiotherapy on fertility

TitleThe effect of chemotherapy and radiotherapy on fertility
化療和放療對生育的影響
Authors
KeywordsChemoradiotherapy
Fertility preservation
Neoplasms
Pregnancy
Radiation injuries
Issue Date2012
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkjr.org
Citation
Hong Kong Journal of Radiology, 2012, v. 15 n. 3, p. 136-142 How to Cite?
AbstractImprovements in cancer treatment have led to increasing numbers of cancer survivors who may desire to have children. Both chemotherapy and radiotherapy can have long-term consequences on reproductive function. Chemotherapeutic agents, especially alkylating agents, are gonadotoxic. Cranial irradiation may cause hypothalamic-pituitary dysfunction and disturb the hormonal regulation of menstruation and fertility. Abdominal or pelvic irradiation has direct toxic effects on the gonads. Female cancer survivors are at risk of premature ovarian failure and adverse pregnancy outcomes. Male survivors are also at risk of subfertility or infertility. This article reviews the effects of chemotherapy and radiotherapy on fertility, pregnancy, and neonatal outcomes of cancer patients.
Persistent Identifierhttp://hdl.handle.net/10722/188983
ISSN
2015 SCImago Journal Rankings: 0.113

 

DC FieldValueLanguage
dc.contributor.authorKwong, DLWen_US
dc.date.accessioned2013-09-17T14:22:28Z-
dc.date.available2013-09-17T14:22:28Z-
dc.date.issued2012en_US
dc.identifier.citationHong Kong Journal of Radiology, 2012, v. 15 n. 3, p. 136-142en_US
dc.identifier.issn2223-6619-
dc.identifier.urihttp://hdl.handle.net/10722/188983-
dc.description.abstractImprovements in cancer treatment have led to increasing numbers of cancer survivors who may desire to have children. Both chemotherapy and radiotherapy can have long-term consequences on reproductive function. Chemotherapeutic agents, especially alkylating agents, are gonadotoxic. Cranial irradiation may cause hypothalamic-pituitary dysfunction and disturb the hormonal regulation of menstruation and fertility. Abdominal or pelvic irradiation has direct toxic effects on the gonads. Female cancer survivors are at risk of premature ovarian failure and adverse pregnancy outcomes. Male survivors are also at risk of subfertility or infertility. This article reviews the effects of chemotherapy and radiotherapy on fertility, pregnancy, and neonatal outcomes of cancer patients.-
dc.languageengen_US
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkjr.orgen_US
dc.relation.ispartofHong Kong Journal of Radiologyen_US
dc.rightsHong Kong Journal of Radiology. Copyright © Hong Kong Academy of Medicine Press.-
dc.subjectChemoradiotherapy-
dc.subjectFertility preservation-
dc.subjectNeoplasms-
dc.subjectPregnancy-
dc.subjectRadiation injuries-
dc.titleThe effect of chemotherapy and radiotherapy on fertilityen_US
dc.title化療和放療對生育的影響-
dc.typeArticleen_US
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_US
dc.identifier.authorityKwong, DLW=rp00414en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.hkuros224297en_US
dc.identifier.volume15en_US
dc.identifier.issue3en_US
dc.identifier.spage136en_US
dc.identifier.epage142en_US
dc.publisher.placeHong Kongen_US

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