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Conference Paper: Improvement of painful bortezomib-induced peripheral neuropathy following acupuncture treatment in a case series of multiple myeloma patients

TitleImprovement of painful bortezomib-induced peripheral neuropathy following acupuncture treatment in a case series of multiple myeloma patients
Authors
KeywordsAcupuncture
Bortezomib
Multiple Myeloma
Peripheral Neuropathy
Issue Date2012
PublisherMary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/publication.aspx?pub_id=233
Citation
The 7th International Auriculotherapy Symposium, Lyon, France, 8-9 June 2012. In Medical Acupuncture, 2012, v. 24 n. 3, p. 181-187 How to Cite?
AbstractBackground: Bortezomib-induced peripheral neuropathy (BIPN) is a common and severe dose-limiting side effect in multiple myeloma (MM) patients. Treatment with narcotics, antidepressants, and anticonvulsants are of limited value in reducing symptoms, and they have the potential for significant side effects. Acupuncture has been reported to be effective in treating neuropathic pain. There has been limited reporting on the effect of acupuncture in treating BIPN. Objective: The aim of this study was to report on the effect of acupuncture in treating BIPN. Design and Patients: This study was a retrospective case series of five MM patients experiencing painful BIPN. Intervention: The patients were treated with the same acupuncture protocol on a weekly basis, adjusted to twice a week or once every 2 weeks based on response. Treatment included insertion of disposable sterile acupuncture needles, which were retained for 25 minutes, at the following bilateral ear points: shen men, point zero, and two auricular points where electro-dermal signal was detected; and bilateral body acupuncture points: LI 4, TE 5, LI 11, ST 40, and Ba Feng in the upper and lower extremities. Main Outcome Measures: All patients were assessed for severity of painful BIPN using a 0-10 numeric pain scale, with one patient assessed using the Clinical Total Neuropathy Score, Functional Assessment of Cancer Therapy-Neurotoxicity questionnaire, and Neuropathy Pain Scale. Results: All five patients experienced immediate pain reduction after one acupuncture treatment. Two of three patients who had more than three acupuncture treatments experienced long-lasting pain reduction and function improvement. There were no adverse events associated with acupuncture. Conclusion: Acupuncture is a viable treatment option for MM patients experiencing painful BIPN. However, further prospective research is needed. © 2012 Mary Ann Liebert, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/188674
ISSN
2015 SCImago Journal Rankings: 0.188
References

 

DC FieldValueLanguage
dc.contributor.authorBao, Ten_US
dc.contributor.authorLao, Len_US
dc.contributor.authorMedeiros, Men_US
dc.contributor.authorZhang, Ren_US
dc.contributor.authorDorsey, SGen_US
dc.contributor.authorBadros, Aen_US
dc.date.accessioned2013-09-03T04:12:04Z-
dc.date.available2013-09-03T04:12:04Z-
dc.date.issued2012en_US
dc.identifier.citationThe 7th International Auriculotherapy Symposium, Lyon, France, 8-9 June 2012. In Medical Acupuncture, 2012, v. 24 n. 3, p. 181-187en_US
dc.identifier.issn1933-6586en_US
dc.identifier.urihttp://hdl.handle.net/10722/188674-
dc.description.abstractBackground: Bortezomib-induced peripheral neuropathy (BIPN) is a common and severe dose-limiting side effect in multiple myeloma (MM) patients. Treatment with narcotics, antidepressants, and anticonvulsants are of limited value in reducing symptoms, and they have the potential for significant side effects. Acupuncture has been reported to be effective in treating neuropathic pain. There has been limited reporting on the effect of acupuncture in treating BIPN. Objective: The aim of this study was to report on the effect of acupuncture in treating BIPN. Design and Patients: This study was a retrospective case series of five MM patients experiencing painful BIPN. Intervention: The patients were treated with the same acupuncture protocol on a weekly basis, adjusted to twice a week or once every 2 weeks based on response. Treatment included insertion of disposable sterile acupuncture needles, which were retained for 25 minutes, at the following bilateral ear points: shen men, point zero, and two auricular points where electro-dermal signal was detected; and bilateral body acupuncture points: LI 4, TE 5, LI 11, ST 40, and Ba Feng in the upper and lower extremities. Main Outcome Measures: All patients were assessed for severity of painful BIPN using a 0-10 numeric pain scale, with one patient assessed using the Clinical Total Neuropathy Score, Functional Assessment of Cancer Therapy-Neurotoxicity questionnaire, and Neuropathy Pain Scale. Results: All five patients experienced immediate pain reduction after one acupuncture treatment. Two of three patients who had more than three acupuncture treatments experienced long-lasting pain reduction and function improvement. There were no adverse events associated with acupuncture. Conclusion: Acupuncture is a viable treatment option for MM patients experiencing painful BIPN. However, further prospective research is needed. © 2012 Mary Ann Liebert, Inc.en_US
dc.languageengen_US
dc.publisherMary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/publication.aspx?pub_id=233en_US
dc.relation.ispartofMedical Acupunctureen_US
dc.subjectAcupunctureen_US
dc.subjectBortezomiben_US
dc.subjectMultiple Myelomaen_US
dc.subjectPeripheral Neuropathyen_US
dc.titleImprovement of painful bortezomib-induced peripheral neuropathy following acupuncture treatment in a case series of multiple myeloma patientsen_US
dc.typeConference_Paperen_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.authorityLao, L=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1089/acu.2011.0868en_US
dc.identifier.scopuseid_2-s2.0-84866278464en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84866278464&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue3en_US
dc.identifier.spage181en_US
dc.identifier.epage187en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridBao, T=23968897400en_US
dc.identifier.scopusauthoridLao, L=7005681883en_US
dc.identifier.scopusauthoridMedeiros, M=55358729500en_US
dc.identifier.scopusauthoridZhang, R=7404864527en_US
dc.identifier.scopusauthoridDorsey, SG=55358672200en_US
dc.identifier.scopusauthoridBadros, A=6701681826en_US
dc.customcontrol.immutablesml 160527 amended-

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