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Conference Paper: Circulating oncometabolite 2-hydroxyglutarate (2HG) as a potential surrogate biomarker in patients with isocitrate dehydrogenase mutant (IDHm) intrahepatic cholangiocarcinoma (ICC)

TitleCirculating oncometabolite 2-hydroxyglutarate (2HG) as a potential surrogate biomarker in patients with isocitrate dehydrogenase mutant (IDHm) intrahepatic cholangiocarcinoma (ICC)
Authors
KeywordsMedical sciences
Oncology medical sciences
Radiology and nuclear medicine pharmacy and pharmacology biology
Cytology and histology
Issue Date2013
PublisherAmerican Society of Clinical Oncology. The Journal's web site is located at http://www.jco.org/
Citation
The 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL., 31 May-4 June 2013. In Journal of Clinical Oncology, 2013, v. 31 n. 15 suppl., abstract no. 4125 How to Cite?
AbstractBACKGROUND: Mutations in the genes encoding for IDH1 and IDH2 occur in 20% of ICC patients (pts), and they lead to the production of the oncometabolite 2HG. We examined whether serum 2HG levels in IDHm ICCpts may 1) serve as a surrogate biomarker for IDH status, 2) correlate with tumor burden, and 3) correlate with circulating proangiogenic biom...
DescriptionGeneral Poster Session - Gastrointestinal (Noncolorectal) Cancer: abstract no. 4125
Open Access Journal
Persistent Identifierhttp://hdl.handle.net/10722/186975
ISSN
2015 Impact Factor: 20.982
2015 SCImago Journal Rankings: 9.204

 

DC FieldValueLanguage
dc.contributor.authorGoyal, Len_US
dc.contributor.authorBorger, DRen_US
dc.contributor.authorYau, Ten_US
dc.contributor.authorPoon, RTPen_US
dc.contributor.authorAncukiewicz, Men_US
dc.contributor.authorChristiani, DCen_US
dc.contributor.authorLiebman, HMen_US
dc.contributor.authorYen, Ken_US
dc.contributor.authorStraley, Ken_US
dc.contributor.authorAgresta, SVen_US
dc.contributor.authorFaris, JEen_US
dc.contributor.authorKwak, ELen_US
dc.contributor.authorClark, JWen_US
dc.contributor.authorRyan, DPen_US
dc.contributor.authorTanabe, Ken_US
dc.contributor.authorDeshpande, Ven_US
dc.contributor.authorJain, RKen_US
dc.contributor.authorIafrate, AJen_US
dc.contributor.authorDuda, DGen_US
dc.contributor.authorZhu, AXen_US
dc.date.accessioned2013-08-20T12:26:29Z-
dc.date.available2013-08-20T12:26:29Z-
dc.date.issued2013en_US
dc.identifier.citationThe 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL., 31 May-4 June 2013. In Journal of Clinical Oncology, 2013, v. 31 n. 15 suppl., abstract no. 4125en_US
dc.identifier.issn0732-183X-
dc.identifier.urihttp://hdl.handle.net/10722/186975-
dc.descriptionGeneral Poster Session - Gastrointestinal (Noncolorectal) Cancer: abstract no. 4125-
dc.descriptionOpen Access Journal-
dc.description.abstractBACKGROUND: Mutations in the genes encoding for IDH1 and IDH2 occur in 20% of ICC patients (pts), and they lead to the production of the oncometabolite 2HG. We examined whether serum 2HG levels in IDHm ICCpts may 1) serve as a surrogate biomarker for IDH status, 2) correlate with tumor burden, and 3) correlate with circulating proangiogenic biom...-
dc.languageengen_US
dc.publisherAmerican Society of Clinical Oncology. The Journal's web site is located at http://www.jco.org/-
dc.relation.ispartofJournal of Clinical Oncologyen_US
dc.subjectMedical sciences-
dc.subjectOncology medical sciences-
dc.subjectRadiology and nuclear medicine pharmacy and pharmacology biology-
dc.subjectCytology and histology-
dc.titleCirculating oncometabolite 2-hydroxyglutarate (2HG) as a potential surrogate biomarker in patients with isocitrate dehydrogenase mutant (IDHm) intrahepatic cholangiocarcinoma (ICC)en_US
dc.typeConference_Paperen_US
dc.identifier.emailYau, T: tyaucc@hku.hken_US
dc.identifier.emailPoon, RTP: poontp@hku.hken_US
dc.identifier.authorityYau, T=rp01466en_US
dc.identifier.authorityPoon, RTP=rp00446en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros217112en_US
dc.identifier.volume31-
dc.identifier.issue15 suppl.-
dc.publisher.placeUnited States-
dc.customcontrol.immutablesml 131016-

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