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Article: Atrial electrical and structural remodeling: implications for racial differences in atrial fibrillation

TitleAtrial electrical and structural remodeling: implications for racial differences in atrial fibrillation
Authors
Issue Date2012
Citation
Journal of Cardiovascular Electrophysiology, 2012, v. 23 suppl. s1, p. s36-s40 How to Cite?
AbstractRacial Disparity in AF Electrophysiology. Racial differences in prevalence and incidence rates of atrial fibrillation (AF) are known to exist even after accounting for ascertainment bias, as well as differences in the prevalence of known risk factors. Thus, a different susceptibility to traditional risk factors in different ethnic groups that lead to AF clearly exists. Initiation and maintenance of AF are dependent on triggers, autonomic influence and atrial substrate, and progression to persistent AF occurs by electromechanical remodeling. Genetic differences among the racial group contribute to such differences. This article reviews the electrophysiologic mechanisms for AF, evidence for racial differences in susceptibility to AF, and suggests possible electromechanical reasons for the susceptibility.
Persistent Identifierhttp://hdl.handle.net/10722/186014
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, CPen_US
dc.contributor.authorTse, HFen_US
dc.contributor.authorSiu, DCWen_US
dc.contributor.authorGbadebo, Den_US
dc.date.accessioned2013-08-20T11:49:59Z-
dc.date.available2013-08-20T11:49:59Z-
dc.date.issued2012en_US
dc.identifier.citationJournal of Cardiovascular Electrophysiology, 2012, v. 23 suppl. s1, p. s36-s40en_US
dc.identifier.urihttp://hdl.handle.net/10722/186014-
dc.description.abstractRacial Disparity in AF Electrophysiology. Racial differences in prevalence and incidence rates of atrial fibrillation (AF) are known to exist even after accounting for ascertainment bias, as well as differences in the prevalence of known risk factors. Thus, a different susceptibility to traditional risk factors in different ethnic groups that lead to AF clearly exists. Initiation and maintenance of AF are dependent on triggers, autonomic influence and atrial substrate, and progression to persistent AF occurs by electromechanical remodeling. Genetic differences among the racial group contribute to such differences. This article reviews the electrophysiologic mechanisms for AF, evidence for racial differences in susceptibility to AF, and suggests possible electromechanical reasons for the susceptibility.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Cardiovascular Electrophysiologyen_US
dc.subject.meshAtrial Fibrillation - ethnology - genetics - pathology - physiopathologyen_US
dc.subject.meshAtrial Functionen_US
dc.subject.meshAutonomic Nervous System - physiopathologyen_US
dc.subject.meshContinental Population Groups - geneticsen_US
dc.subject.meshHealth Status Disparitiesen_US
dc.titleAtrial electrical and structural remodeling: implications for racial differences in atrial fibrillationen_US
dc.typeArticleen_US
dc.identifier.emailLau, CP: cplau@hku.hken_US
dc.identifier.emailTse, HF: hftse@hkucc.hku.hken_US
dc.identifier.emailSiu, DCW: cwdsiu@hkucc.hku.hken_US
dc.identifier.authorityTse, HF=rp00428en_US
dc.identifier.authoritySiu, DCW=rp00534en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/jce.12022en_US
dc.identifier.pmid23140346en_US
dc.identifier.hkuros218498en_US
dc.identifier.hkuros224336-
dc.identifier.volume23en_US
dc.identifier.issuesuppl. s1-
dc.identifier.spages36en_US
dc.identifier.epages40en_US
dc.identifier.isiWOS:000310973300008-

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