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Article: The relationship between the human spermatozoa hypo-osmotic swelling test and the human spermatozoa zona-free hamster ova penetration bioassay

TitleThe relationship between the human spermatozoa hypo-osmotic swelling test and the human spermatozoa zona-free hamster ova penetration bioassay
Authors
Issue Date1985
Citation
Ircs Medical Science, 1985, v. 13 n. 5, p. 437-438 How to Cite?
AbstractGeneral semen analysis alone cannot ascertain spermatozoal fertilizing ability which is commonly determined by the human sperm zona-free hamster ova penetration assay. This is expensive and time-consuming and thus an alternative test for male fertility is desirable. Jeyendran et al. recently reported a significant correlation between the swelling of fertile human sperm exposed to hypo-osmotic shock and fertilization of zona-free hamster ova. It is assumed that human sperm hypo-osmotic swelling reflects functional integrity of the sperm membrane, which may also be a test for spermatozoal fertilizing ability. In the present study, 148 semen samples from the husbands of infertile couples were subjected to general semen analysis, the hypo-osmotic swelling test and the hamster ova assay. No significant correlation was found between spermatozoal swelling and zona-free hamster egg penetration, from which we conclude that the two tests are apparently evaluating non-associated functional qualities of spermatozoa.
Persistent Identifierhttp://hdl.handle.net/10722/184173
ISSN

 

DC FieldValueLanguage
dc.contributor.authorChan, SYWen_US
dc.contributor.authorFox, EJen_US
dc.contributor.authorTang, LCHen_US
dc.date.accessioned2013-06-25T03:01:00Z-
dc.date.available2013-06-25T03:01:00Z-
dc.date.issued1985en_US
dc.identifier.citationIrcs Medical Science, 1985, v. 13 n. 5, p. 437-438en_US
dc.identifier.issn0305-6651en_US
dc.identifier.urihttp://hdl.handle.net/10722/184173-
dc.description.abstractGeneral semen analysis alone cannot ascertain spermatozoal fertilizing ability which is commonly determined by the human sperm zona-free hamster ova penetration assay. This is expensive and time-consuming and thus an alternative test for male fertility is desirable. Jeyendran et al. recently reported a significant correlation between the swelling of fertile human sperm exposed to hypo-osmotic shock and fertilization of zona-free hamster ova. It is assumed that human sperm hypo-osmotic swelling reflects functional integrity of the sperm membrane, which may also be a test for spermatozoal fertilizing ability. In the present study, 148 semen samples from the husbands of infertile couples were subjected to general semen analysis, the hypo-osmotic swelling test and the hamster ova assay. No significant correlation was found between spermatozoal swelling and zona-free hamster egg penetration, from which we conclude that the two tests are apparently evaluating non-associated functional qualities of spermatozoa.en_US
dc.languageengen_US
dc.relation.ispartofIRCS Medical Scienceen_US
dc.titleThe relationship between the human spermatozoa hypo-osmotic swelling test and the human spermatozoa zona-free hamster ova penetration bioassayen_US
dc.typeArticleen_US
dc.identifier.emailTang, LCH: lchtang@hku.hken_US
dc.identifier.authorityTang, LCH=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0021999115en_US
dc.identifier.volume13en_US
dc.identifier.issue5en_US
dc.identifier.spage437en_US
dc.identifier.epage438en_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US
dc.identifier.scopusauthoridFox, EJ=7202093823en_US
dc.identifier.scopusauthoridTang, LCH=7402081111en_US

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