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Article: Hyperprolactinaemic amenorrhoea in Hong Kong

TitleHyperprolactinaemic amenorrhoea in Hong Kong
Authors
Issue Date1983
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOG
Citation
Australian And New Zealand Journal Of Obstetrics And Gynaecology, 1983, v. 23 n. 3, p. 165-169 How to Cite?
AbstractIn a retrospective study of 595 patients attending the Menstrual Disorder Clinic from January, 1978 to December, 1981, 92 patients (15.5%) had raised serum prolactin (PRL) levels (>25 ng/ml) on 2 or more separate occasions with a mean (±S.E.M.) value of 67.1 ± 2.5 ng/ml. Galactorrhoea was found in 27.2% of the hyperprolactinaemic patients. Primary amenorrhoea was observed in 1 patient (1.1%) with serum PRL level of 68 ng/ml. Secondary amenorrhoea of longer than 6 months' duration occurred in 61 patients (66.3%) with mean PRL level 84.2 ± 3.3 ng/ml. The 30 patients (32.6%) with irregular menstruation had a mean PRL level of 47.2 ± 3.3 ng/ml. Investigations revealed that 43 patients (46.7%) had idiopathic hyperprolactinaemia, 14 patients (15.4%) had drug induced hyperprolactinaemia and 1 patient (1.1%) had hypothyroidism; 18 patients (19.5%) had suspected pituitary microadenoma and 16 patients (17.2%) had abnormal radiographic findings. Bromocriptine treatment was given to 38 patients, 13 with abnormal tomographic findings (mean serum PRL > 100 ng/ml); 18 with suspected pituitary microadenoma (mean serum PRL 94 ± 2.7 ng/ml) and 7 with idiopathic hyperprolactinaemia (mean serum PRL 65 ± 4.7 ng/ml). All patients (38/38) responded to treatment with restoration of menstruation and cessation of galactorrhoea with 1 to 3 months. Mean PRL level was 21.6 ± 5.2 ng/ml at the time of response. Thirteen patients subsequently became pregnant and all delivered healthy babies.
Persistent Identifierhttp://hdl.handle.net/10722/184148
ISSN
2015 Impact Factor: 1.738
2015 SCImago Journal Rankings: 0.814
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTang, LCHen_US
dc.contributor.authorSung, MLen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2013-06-25T03:00:44Z-
dc.date.available2013-06-25T03:00:44Z-
dc.date.issued1983en_US
dc.identifier.citationAustralian And New Zealand Journal Of Obstetrics And Gynaecology, 1983, v. 23 n. 3, p. 165-169en_US
dc.identifier.issn0004-8666en_US
dc.identifier.urihttp://hdl.handle.net/10722/184148-
dc.description.abstractIn a retrospective study of 595 patients attending the Menstrual Disorder Clinic from January, 1978 to December, 1981, 92 patients (15.5%) had raised serum prolactin (PRL) levels (>25 ng/ml) on 2 or more separate occasions with a mean (±S.E.M.) value of 67.1 ± 2.5 ng/ml. Galactorrhoea was found in 27.2% of the hyperprolactinaemic patients. Primary amenorrhoea was observed in 1 patient (1.1%) with serum PRL level of 68 ng/ml. Secondary amenorrhoea of longer than 6 months' duration occurred in 61 patients (66.3%) with mean PRL level 84.2 ± 3.3 ng/ml. The 30 patients (32.6%) with irregular menstruation had a mean PRL level of 47.2 ± 3.3 ng/ml. Investigations revealed that 43 patients (46.7%) had idiopathic hyperprolactinaemia, 14 patients (15.4%) had drug induced hyperprolactinaemia and 1 patient (1.1%) had hypothyroidism; 18 patients (19.5%) had suspected pituitary microadenoma and 16 patients (17.2%) had abnormal radiographic findings. Bromocriptine treatment was given to 38 patients, 13 with abnormal tomographic findings (mean serum PRL > 100 ng/ml); 18 with suspected pituitary microadenoma (mean serum PRL 94 ± 2.7 ng/ml) and 7 with idiopathic hyperprolactinaemia (mean serum PRL 65 ± 4.7 ng/ml). All patients (38/38) responded to treatment with restoration of menstruation and cessation of galactorrhoea with 1 to 3 months. Mean PRL level was 21.6 ± 5.2 ng/ml at the time of response. Thirteen patients subsequently became pregnant and all delivered healthy babies.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOGen_US
dc.relation.ispartofAustralian and New Zealand Journal of Obstetrics and Gynaecologyen_US
dc.subject.meshAdenoma - Complicationsen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAmenorrhea - Drug Therapy - Etiologyen_US
dc.subject.meshBromocriptine - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshGalactorrhea - Drug Therapy - Etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHypothyroidism - Complicationsen_US
dc.subject.meshInfertility, Female - Drug Therapy - Etiologyen_US
dc.subject.meshLactation Disorders - Drug Therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshPituitary Neoplasms - Complicationsen_US
dc.subject.meshPregnancyen_US
dc.subject.meshProlactin - Blooden_US
dc.titleHyperprolactinaemic amenorrhoea in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailTang, LCH: lchtang@hku.hken_US
dc.identifier.authorityTang, LCH=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1479-828X.1983.tb00568.x-
dc.identifier.pmid6580885en_US
dc.identifier.scopuseid_2-s2.0-0020519834en_US
dc.identifier.volume23en_US
dc.identifier.issue3en_US
dc.identifier.spage165en_US
dc.identifier.epage169en_US
dc.identifier.isiWOS:A1983RH65000009-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridTang, LCH=7402081111en_US
dc.identifier.scopusauthoridSung, ML=36874592900en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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