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Conference Paper: FBXO31 functions as an oncoprotein by suppressing apoptosis via regulation of MAPK pathway in esophageal squamous cell carcioma cell lines

TitleFBXO31 functions as an oncoprotein by suppressing apoptosis via regulation of MAPK pathway in esophageal squamous cell carcioma cell lines
Authors
Liu, JLi, BTsao, GSWCheung, ALM
KeywordsMedical sciences
Oncology
Issue Date2013
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8 suppl. 1, abstract no. 4305 How to Cite?
DOI: http://dx.doi.org/10.1158/1538-7445.AM2013-4305
AbstractFBXO31 is a DNA-damage responsive F-box protein, found to be down-regulated in breast and hepatocellular carcinoma but up-regulated in esophageal squamous cell carcinoma. The role of FBXO31 in carcinogenesis is not fully determined. Mitogen activated protein kinases (MAPKs) play pivotal role in cellular response to diverse stresses, and are involved in regulating cell proliferation, differentiation and apoptosis. In this study, data from gain-of-function and loss-of-function experiments revealed that FBXO31 regulated cell apoptosis upon UV stress, as evidenced by changes in expressions of ...
DescriptionPoster Presentations - Signaling Pathways in Cancer Cells: abstract no. 4305
Persistent Identifierhttp://hdl.handle.net/10722/183894
ISSN
0008-5472
2021 Impact Factor: 13.312
2020 SCImago Journal Rankings: 4.103

 

DC FieldValueLanguage
dc.contributor.authorLiu, Jen_US
dc.contributor.authorLi, Ben_US
dc.contributor.authorTsao, GSWen_US
dc.contributor.authorCheung, ALMen_US
dc.date.accessioned2013-06-18T04:23:45Z-
dc.date.available2013-06-18T04:23:45Z-
dc.date.issued2013en_US
dc.identifier.citationThe 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8 suppl. 1, abstract no. 4305en_US
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/183894-
dc.descriptionPoster Presentations - Signaling Pathways in Cancer Cells: abstract no. 4305-
dc.description.abstractFBXO31 is a DNA-damage responsive F-box protein, found to be down-regulated in breast and hepatocellular carcinoma but up-regulated in esophageal squamous cell carcinoma. The role of FBXO31 in carcinogenesis is not fully determined. Mitogen activated protein kinases (MAPKs) play pivotal role in cellular response to diverse stresses, and are involved in regulating cell proliferation, differentiation and apoptosis. In this study, data from gain-of-function and loss-of-function experiments revealed that FBXO31 regulated cell apoptosis upon UV stress, as evidenced by changes in expressions of ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/-
dc.relation.ispartofCancer Researchen_US
dc.subjectMedical sciences-
dc.subjectOncology-
dc.titleFBXO31 functions as an oncoprotein by suppressing apoptosis via regulation of MAPK pathway in esophageal squamous cell carcioma cell linesen_US
dc.typeConference_Paperen_US
dc.identifier.emailLi, B: libinhku@hkucc.hku.hken_US
dc.identifier.emailTsao, GSW: gswtsao@hku.hken_US
dc.identifier.emailCheung, ALM: lmcheung@hku.hken_US
dc.identifier.authorityTsao, GSW=rp00399en_US
dc.identifier.authorityCheung, ALM=rp00332en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1158/1538-7445.AM2013-4305-
dc.identifier.hkuros214814en_US
dc.identifier.volume73en_US
dc.identifier.issue8 suppl. 1-
dc.publisher.placeUnited States-
dc.identifier.issnl0008-5472-

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