File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Relationship of retinal vascular caliber with retinal nerve fiber layer thickness: The singapore malay eye study

TitleRelationship of retinal vascular caliber with retinal nerve fiber layer thickness: The singapore malay eye study
Authors
Issue Date2009
PublisherAssociation for Research in Vision and Ophthalmology. The Journal's web site is located at http://www.iovs.org
Citation
Investigative Ophthalmology And Visual Science, 2009, v. 50 n. 9, p. 4091-4096 How to Cite?
AbstractPURPOSE. To describe the relationship of retinal arteriolar and venular caliber with retinal nerve fiber layer (RNFL) thickness. METHODS. A population-based, cross-sectional study of Malay persons aged 40 to 80 years residing in Singapore was conducted from 2004 to 2006. Retinal arteriolar and venular calibers were measured with a computer-based technique according to a validated, standardized protocol. RNFL was assessed with retinal tomography. RESULTS. There were 2706 persons with gradable retinal photographs and HRT images of acceptable quality available for analysis. In linear regression models that adjusted for age, sex, diabetes, body mass index, intraocular pressure, and other factors, each standard deviation decrease in arteriolar and venular caliber was associated with a 5.81- and 8.37-μm decrease, respectively, in mean global RNFL thickness (both P <0.001). These associations remained similar after persons with glaucoma were excluded. In persons with glaucoma, retinal venular caliber was independently associated with the temporal and temporal-to-inferior region of mean RNFL thickness in multivariate analysis; each SD decrease in retinal venular diameter was associated with an 8.54-μm decrease in the temporal region (P < 0.022), and a 38.32-μm decrease in the temporalto-inferior region (P < 0.006) of mean RNFL thickness. CONCLUSIONS. Narrower retinal vessel caliber was associated with reduced RNFL thickness in this Asian population. © Association for Research in Vision and Ophthalmology.
Persistent Identifierhttp://hdl.handle.net/10722/183578
ISSN
2015 Impact Factor: 3.427
2015 SCImago Journal Rankings: 2.008
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZheng, Yen_US
dc.contributor.authorCheung, Nen_US
dc.contributor.authorAung, Ten_US
dc.contributor.authorMitchell, Pen_US
dc.contributor.authorHe, Men_US
dc.contributor.authorWong, TYen_US
dc.date.accessioned2013-05-28T06:14:54Z-
dc.date.available2013-05-28T06:14:54Z-
dc.date.issued2009en_US
dc.identifier.citationInvestigative Ophthalmology And Visual Science, 2009, v. 50 n. 9, p. 4091-4096en_US
dc.identifier.issn0146-0404en_US
dc.identifier.urihttp://hdl.handle.net/10722/183578-
dc.description.abstractPURPOSE. To describe the relationship of retinal arteriolar and venular caliber with retinal nerve fiber layer (RNFL) thickness. METHODS. A population-based, cross-sectional study of Malay persons aged 40 to 80 years residing in Singapore was conducted from 2004 to 2006. Retinal arteriolar and venular calibers were measured with a computer-based technique according to a validated, standardized protocol. RNFL was assessed with retinal tomography. RESULTS. There were 2706 persons with gradable retinal photographs and HRT images of acceptable quality available for analysis. In linear regression models that adjusted for age, sex, diabetes, body mass index, intraocular pressure, and other factors, each standard deviation decrease in arteriolar and venular caliber was associated with a 5.81- and 8.37-μm decrease, respectively, in mean global RNFL thickness (both P <0.001). These associations remained similar after persons with glaucoma were excluded. In persons with glaucoma, retinal venular caliber was independently associated with the temporal and temporal-to-inferior region of mean RNFL thickness in multivariate analysis; each SD decrease in retinal venular diameter was associated with an 8.54-μm decrease in the temporal region (P < 0.022), and a 38.32-μm decrease in the temporalto-inferior region (P < 0.006) of mean RNFL thickness. CONCLUSIONS. Narrower retinal vessel caliber was associated with reduced RNFL thickness in this Asian population. © Association for Research in Vision and Ophthalmology.en_US
dc.languageengen_US
dc.publisherAssociation for Research in Vision and Ophthalmology. The Journal's web site is located at http://www.iovs.orgen_US
dc.relation.ispartofInvestigative Ophthalmology and Visual Scienceen_US
dc.titleRelationship of retinal vascular caliber with retinal nerve fiber layer thickness: The singapore malay eye studyen_US
dc.typeArticleen_US
dc.identifier.emailCheung, N: dannycheung@hotmail.comen_US
dc.identifier.authorityCheung, N=rp01752en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1167/iovs.09-3444en_US
dc.identifier.pmid19443726-
dc.identifier.scopuseid_2-s2.0-70349263458en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70349263458&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume50en_US
dc.identifier.issue9en_US
dc.identifier.spage4091en_US
dc.identifier.epage4096en_US
dc.identifier.isiWOS:000269438400009-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridZheng, Y=16240506800en_US
dc.identifier.scopusauthoridCheung, N=8054683900en_US
dc.identifier.scopusauthoridAung, T=26643141900en_US
dc.identifier.scopusauthoridMitchell, P=7402933815en_US
dc.identifier.scopusauthoridHe, M=15765257500en_US
dc.identifier.scopusauthoridWong, TY=7403531208en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats