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Article: BMI and retinal vascular caliber in children

TitleBMI and retinal vascular caliber in children
Authors
Issue Date2007
PublisherNorth American Association for the Study of Obesity. The Journal's web site is located at http://www.obesityresearch.org
Citation
Obesity, 2007, v. 15 n. 1, p. 209-215 How to Cite?
AbstractObjective: In adult populations, changes in retinal vascular caliber have been linked with obesity and metabolic syndrome. We examined the association of BMI and weight with retinal vascular caliber in children. Research Methods and Procedures: This was a school-based, cross-sectional study of 768 children, 7 to 9 years old, randomly sampled from the Singapore Cohort Study of the Risk Factors for Myopia. Participants had digital retinal photographs. Retinal vascular caliber was measured using a computer-based program and combined to provide average calibers of arterioles and venules in that eye. Weight and height were measured using standardized protocol. These data were used to calculate BMI. Results: In this population, the mean retinal arteriolar and venular calibers were 156.40 μm [95% confidence interval (CI), 155.44 to 157.36] and 225.43 μm (95% CI, 224.10 to 226.74) respectively. After controlling for age, gender, race, parental monthly income, axial length, birth weight, and birth length, each 3.1 kg/m2 (standard deviation) increase in BMI was associated with a 2.55-μm (95% CI, 1.21 to 3.89; p < 0.001) larger retinal venular caliber. In multivariable analysis, greater weight was also significantly associated with larger retinal venular caliber. BMI and weight were not associated with retinal arteriolar caliber. Height was not significantly associated with retinal arteriolar or venular caliber. Discussion: Greater BMI and weight are associated with larger retinal venular caliber in healthy children. Copyright © 2007 NAASO.
Persistent Identifierhttp://hdl.handle.net/10722/183514
ISSN
2015 Impact Factor: 3.614
2015 SCImago Journal Rankings: 2.016
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, Nen_US
dc.contributor.authorSaw, SMen_US
dc.contributor.authorIslam, FMAen_US
dc.contributor.authorRogers, SLen_US
dc.contributor.authorShankar, Aen_US
dc.contributor.authorDe Haseth, Ken_US
dc.contributor.authorMitchell, Pen_US
dc.contributor.authorWong, TYen_US
dc.date.accessioned2013-05-28T06:14:18Z-
dc.date.available2013-05-28T06:14:18Z-
dc.date.issued2007en_US
dc.identifier.citationObesity, 2007, v. 15 n. 1, p. 209-215en_US
dc.identifier.issn1930-7381en_US
dc.identifier.urihttp://hdl.handle.net/10722/183514-
dc.description.abstractObjective: In adult populations, changes in retinal vascular caliber have been linked with obesity and metabolic syndrome. We examined the association of BMI and weight with retinal vascular caliber in children. Research Methods and Procedures: This was a school-based, cross-sectional study of 768 children, 7 to 9 years old, randomly sampled from the Singapore Cohort Study of the Risk Factors for Myopia. Participants had digital retinal photographs. Retinal vascular caliber was measured using a computer-based program and combined to provide average calibers of arterioles and venules in that eye. Weight and height were measured using standardized protocol. These data were used to calculate BMI. Results: In this population, the mean retinal arteriolar and venular calibers were 156.40 μm [95% confidence interval (CI), 155.44 to 157.36] and 225.43 μm (95% CI, 224.10 to 226.74) respectively. After controlling for age, gender, race, parental monthly income, axial length, birth weight, and birth length, each 3.1 kg/m2 (standard deviation) increase in BMI was associated with a 2.55-μm (95% CI, 1.21 to 3.89; p < 0.001) larger retinal venular caliber. In multivariable analysis, greater weight was also significantly associated with larger retinal venular caliber. BMI and weight were not associated with retinal arteriolar caliber. Height was not significantly associated with retinal arteriolar or venular caliber. Discussion: Greater BMI and weight are associated with larger retinal venular caliber in healthy children. Copyright © 2007 NAASO.en_US
dc.languageengen_US
dc.publisherNorth American Association for the Study of Obesity. The Journal's web site is located at http://www.obesityresearch.orgen_US
dc.relation.ispartofObesityen_US
dc.subject.meshArterioles - Pathologyen_US
dc.subject.meshBody Mass Indexen_US
dc.subject.meshChilden_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshConfidence Intervalsen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshMyopia - Epidemiology - Ethnology - Etiologyen_US
dc.subject.meshObesity - Ethnology - Pathology - Physiopathologyen_US
dc.subject.meshOdds Ratioen_US
dc.subject.meshPhotographyen_US
dc.subject.meshRetinal Artery - Pathologyen_US
dc.subject.meshRetinal Diseases - Epidemiologyen_US
dc.subject.meshRetinal Vein - Pathologyen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSingaporeen_US
dc.subject.meshVenules - Pathologyen_US
dc.titleBMI and retinal vascular caliber in childrenen_US
dc.typeArticleen_US
dc.identifier.emailCheung, N: dannycheung@hotmail.comen_US
dc.identifier.authorityCheung, N=rp01752en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1038/oby.2007.576en_US
dc.identifier.pmid17228049-
dc.identifier.scopuseid_2-s2.0-33846883513en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846883513&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume15en_US
dc.identifier.issue1en_US
dc.identifier.spage209en_US
dc.identifier.epage215en_US
dc.identifier.isiWOS:000249605500026-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridCheung, N=8054683900en_US
dc.identifier.scopusauthoridSaw, SM=7006402006en_US
dc.identifier.scopusauthoridIslam, FMA=35446440500en_US
dc.identifier.scopusauthoridRogers, SL=12768398500en_US
dc.identifier.scopusauthoridShankar, A=12138932300en_US
dc.identifier.scopusauthoridDe Haseth, K=15841326700en_US
dc.identifier.scopusauthoridMitchell, P=7402933815en_US
dc.identifier.scopusauthoridWong, TY=7403531208en_US

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