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Conference Paper: Diabetic retinopathy

TitleDiabetic retinopathy
Authors
Issue Date2010
PublisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lancet
Citation
The Lancet, 2010, v. 376 n. 9735, p. 124-136 How to Cite?
AbstractDiabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising.
Persistent Identifierhttp://hdl.handle.net/10722/183471
ISSN
2015 Impact Factor: 44.002
2015 SCImago Journal Rankings: 14.638
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, Nen_US
dc.contributor.authorMitchell, Pen_US
dc.contributor.authorWong, TYen_US
dc.date.accessioned2013-05-28T06:13:43Z-
dc.date.available2013-05-28T06:13:43Z-
dc.date.issued2010en_US
dc.identifier.citationThe Lancet, 2010, v. 376 n. 9735, p. 124-136en_US
dc.identifier.issn0140-6736en_US
dc.identifier.urihttp://hdl.handle.net/10722/183471-
dc.description.abstractDiabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising.en_US
dc.languageengen_US
dc.publisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lanceten_US
dc.relation.ispartofThe Lanceten_US
dc.subject.meshDiabetic Retinopathy - Diagnosis - Physiopathology - Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshRisk Factorsen_US
dc.titleDiabetic retinopathyen_US
dc.typeConference_Paperen_US
dc.identifier.emailCheung, N: dannycheung@hotmail.comen_US
dc.identifier.authorityCheung, N=rp01752en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0140-6736(09)62124-3en_US
dc.identifier.pmid20580421-
dc.identifier.scopuseid_2-s2.0-77955013602en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77955013602&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume376en_US
dc.identifier.issue9735en_US
dc.identifier.spage124en_US
dc.identifier.epage136en_US
dc.identifier.isiWOS:000279943200028-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridCheung, N=8054683900en_US
dc.identifier.scopusauthoridMitchell, P=7402933815en_US
dc.identifier.scopusauthoridWong, TY=7403531208en_US

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