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Conference Paper: Radical versus partial nephrectomy for T1 renal cancer: equivalent oncological outcome with better renal preservation

TitleRadical versus partial nephrectomy for T1 renal cancer: equivalent oncological outcome with better renal preservation
Authors
Issue Date2012
PublisherHong Kong Urological Association (HKUA).
Citation
The 23rd Video Urology World Congress (VUWC2012) - Annual Scientific Meeting of the Hong Kong Urological Association (HKUA 2012), Hong Kong, 8-11 November 2012. In Abstracts of the HKUA 2012 Annual Scientific Meeting, 2012, p. 6, abstract 19 How to Cite?
AbstractOBJECTIVE: To examine and compare the outcome of radical and partial nephrectomy for T1 renal cancer (≤7 cm) in our centre. PATIENTS AND METHOD: Between January 2005 and December 2010, 38 (44.2%) radical nephrectomies (RN) and 48 (55.8%) partial nephrectomies (PN) were performed for solitary, T1 renal cancer in patients with normal contralateral kidney. GFR was estimated with the Modification of Diet in Renal Disease (MDRD) formula. CKD was defined as GFR lower than 60 mL/min per 1.73 m2. Cox regression model was used to compare overall survival and new onset of CKD. RESULTS: At last follow-up 32 RN patients (84.2%) and 43 PN patients (89.6%) were alive. There was no significant difference in overall survival between RN and PN patients (hazard ratio, 0.673; 95% confidence interval [CI], 0.128–3.529; p = 0.64). 1 RN patient (2.6%) developed systemic metastasis. RN patients had significantly higher reduction rate in GFR (35.4% vs 12.6%, p = 0.000), and higher risk in developing CKD (hazard ratio, 6.308; 95% CI, 2.074–19.189, p = 0.001). CONCLUSION: Relative to RN in managing T1 renal cancer, PN has equivalent survival and oncological clearance, with superiority in renal preservation and lower incidence of new CKD onset. PN should be the treatment of choice for T1 renal cancer.
Persistent Identifierhttp://hdl.handle.net/10722/181134

 

DC FieldValueLanguage
dc.contributor.authorLai, TCTen_US
dc.contributor.authorWong, EMHen_US
dc.contributor.authorHo, KLen_US
dc.contributor.authorTam, PCen_US
dc.contributor.authorYiu, MKen_US
dc.date.accessioned2013-02-19T11:36:57Z-
dc.date.available2013-02-19T11:36:57Z-
dc.date.issued2012en_US
dc.identifier.citationThe 23rd Video Urology World Congress (VUWC2012) - Annual Scientific Meeting of the Hong Kong Urological Association (HKUA 2012), Hong Kong, 8-11 November 2012. In Abstracts of the HKUA 2012 Annual Scientific Meeting, 2012, p. 6, abstract 19en_US
dc.identifier.urihttp://hdl.handle.net/10722/181134-
dc.description.abstractOBJECTIVE: To examine and compare the outcome of radical and partial nephrectomy for T1 renal cancer (≤7 cm) in our centre. PATIENTS AND METHOD: Between January 2005 and December 2010, 38 (44.2%) radical nephrectomies (RN) and 48 (55.8%) partial nephrectomies (PN) were performed for solitary, T1 renal cancer in patients with normal contralateral kidney. GFR was estimated with the Modification of Diet in Renal Disease (MDRD) formula. CKD was defined as GFR lower than 60 mL/min per 1.73 m2. Cox regression model was used to compare overall survival and new onset of CKD. RESULTS: At last follow-up 32 RN patients (84.2%) and 43 PN patients (89.6%) were alive. There was no significant difference in overall survival between RN and PN patients (hazard ratio, 0.673; 95% confidence interval [CI], 0.128–3.529; p = 0.64). 1 RN patient (2.6%) developed systemic metastasis. RN patients had significantly higher reduction rate in GFR (35.4% vs 12.6%, p = 0.000), and higher risk in developing CKD (hazard ratio, 6.308; 95% CI, 2.074–19.189, p = 0.001). CONCLUSION: Relative to RN in managing T1 renal cancer, PN has equivalent survival and oncological clearance, with superiority in renal preservation and lower incidence of new CKD onset. PN should be the treatment of choice for T1 renal cancer.-
dc.languageengen_US
dc.publisherHong Kong Urological Association (HKUA).-
dc.relation.ispartofAbstracts of the Hong Kong Urological Association Annual Scientific Meeting 11 November 2012, Hong Kongen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleRadical versus partial nephrectomy for T1 renal cancer: equivalent oncological outcome with better renal preservationen_US
dc.typeConference_Paperen_US
dc.identifier.emailHo, KL: hkl218@hkucc.hku.hken_US
dc.identifier.emailTam, PC: hrmstpc@hkucc.hku.hken_US
dc.identifier.emailYiu, MK: pmkyiu@hku.hken_US
dc.description.naturepostprint-
dc.identifier.hkuros213179en_US
dc.identifier.spage6-
dc.identifier.epage6-
dc.publisher.placeHong Kong-

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