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Article: Prenatal evaluation of facial clefts by three-dimensional extended imaging

TitlePrenatal evaluation of facial clefts by three-dimensional extended imaging
Authors
Issue Date2007
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
Citation
Prenatal Diagnosis, 2007, v. 27 n. 8, p. 722-729 How to Cite?
AbstractObjectives: To determine the prenatal diagnostic accuracy of two-dimensional ultrasound (2DUS) alone versus 2DUS in conjunction with three-dimensional ultrasonography (3DUS) including orthogonal display (OGD) and three-dimensional extended Imaging for cleft lip and primary palate. Materials and Method: Fetuses being suspected of having a facial cleft by previous ultrasound examination or family history were examined sequentially with 2DUS and then 3DUS. Results: Of a total of 30 infants, 22 had cleft lip and nine also had cleft palate at birth. The use of 2DUS with or without 3DUS correctly identified all cases of cleft lips prenatally. However, the use of 2DUS in conjunction with 3DUS correctly identified more cleft primary palate than 2DUS alone (88.9% vs 22.2%, P < 0.01). Cleft primary palate was well demonstrated in both the multi-slice view (MSV)™ and OGD modes. In one case, a cleft palate was shown in the MSV™ mode but not in the Oblique view™ (OBV)™ mode. All the unaffected fetuses were reported as no cleft palate with the use of MSV™ mode. Conclusions: Combined approach of 2DUS and 3DUS with both OGD and MSV™ modes significantly improved the prenatal detection rate for a cleft palate compared with 2DUS alone (88.9% vs 22.2%) without decreasing the specificity. Copyright © 2007 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/180688
ISSN
2015 Impact Factor: 3.043
2015 SCImago Journal Rankings: 1.450
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWang, LMen_US
dc.contributor.authorLeung, KYen_US
dc.contributor.authorTang, Men_US
dc.date.accessioned2013-01-28T01:41:07Z-
dc.date.available2013-01-28T01:41:07Z-
dc.date.issued2007en_US
dc.identifier.citationPrenatal Diagnosis, 2007, v. 27 n. 8, p. 722-729en_US
dc.identifier.issn0197-3851en_US
dc.identifier.urihttp://hdl.handle.net/10722/180688-
dc.description.abstractObjectives: To determine the prenatal diagnostic accuracy of two-dimensional ultrasound (2DUS) alone versus 2DUS in conjunction with three-dimensional ultrasonography (3DUS) including orthogonal display (OGD) and three-dimensional extended Imaging for cleft lip and primary palate. Materials and Method: Fetuses being suspected of having a facial cleft by previous ultrasound examination or family history were examined sequentially with 2DUS and then 3DUS. Results: Of a total of 30 infants, 22 had cleft lip and nine also had cleft palate at birth. The use of 2DUS with or without 3DUS correctly identified all cases of cleft lips prenatally. However, the use of 2DUS in conjunction with 3DUS correctly identified more cleft primary palate than 2DUS alone (88.9% vs 22.2%, P < 0.01). Cleft primary palate was well demonstrated in both the multi-slice view (MSV)™ and OGD modes. In one case, a cleft palate was shown in the MSV™ mode but not in the Oblique view™ (OBV)™ mode. All the unaffected fetuses were reported as no cleft palate with the use of MSV™ mode. Conclusions: Combined approach of 2DUS and 3DUS with both OGD and MSV™ modes significantly improved the prenatal detection rate for a cleft palate compared with 2DUS alone (88.9% vs 22.2%) without decreasing the specificity. Copyright © 2007 John Wiley & Sons, Ltd.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252en_US
dc.relation.ispartofPrenatal Diagnosisen_US
dc.subject.meshAdulten_US
dc.subject.meshCleft Lip - Embryology - Ultrasonographyen_US
dc.subject.meshCleft Palate - Embryology - Ultrasonographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFetal Diseases - Ultrasonographyen_US
dc.subject.meshHumansen_US
dc.subject.meshImaging, Three-Dimensionalen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshPregnancyen_US
dc.subject.meshReproducibility Of Resultsen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshUltrasonography, Prenatal - Methodsen_US
dc.titlePrenatal evaluation of facial clefts by three-dimensional extended imagingen_US
dc.typeArticleen_US
dc.identifier.emailTang, M: mhytang@hkucc.hku.hken_US
dc.identifier.authorityTang, M=rp01701en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/pd.1766en_US
dc.identifier.pmid17533633-
dc.identifier.scopuseid_2-s2.0-34547742646en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34547742646&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume27en_US
dc.identifier.issue8en_US
dc.identifier.spage722en_US
dc.identifier.epage729en_US
dc.identifier.isiWOS:000248971900007-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridWang, LM=18438905100en_US
dc.identifier.scopusauthoridLeung, KY=8247106900en_US
dc.identifier.scopusauthoridTang, M=35362943900en_US

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