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Article: Second-trimester hydrops fetalis in pregnancies affected by homozygous α-thalassaemia-1

TitleSecond-trimester hydrops fetalis in pregnancies affected by homozygous α-thalassaemia-1
Authors
Issue Date1997
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
Citation
Prenatal Diagnosis, 1997, v. 17 n. 3, p. 267-269 How to Cite?
AbstractHomozygous α-thalassaemia-1 is the commonest cause of hydrops fetalis in South-East Asia. Ultrasonographic features of hydrops fetalis were said to be evident only after 20 weeks of gestation. We studied 111 pregnancies at risk of homozygous α-thalassaemia-1 at 12-14 gestational weeks and 101 pregnancies at 17-18 weeks by abdominal ultrasound examination. Ultrasonographic features of hydrops fetalis were seen in 3 out of 44 pregnancies affected by homozygous α-thalassaemia-1 at 12-14 weeks [7 per cent; 95 per cent confidence interval (CI) 1-19 per cent] and in 7 out of 21 affected pregnancies at 17-18 weeks (33 per cent; 95 per cent CI 15-57 per cent). In conclusion, homozygous α-thalassaemia-1 can cause hydrops fetalis in the early second trimester. It should constitute one of the differential diagnoses in the work-up of second-trimester hydrops fetalis.
Persistent Identifierhttp://hdl.handle.net/10722/180624
ISSN
2015 Impact Factor: 3.043
2015 SCImago Journal Rankings: 1.450
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, YHen_US
dc.contributor.authorGhosh, Aen_US
dc.contributor.authorTang, MHYen_US
dc.contributor.authorLee, CPen_US
dc.contributor.authorSin, SYen_US
dc.date.accessioned2013-01-28T01:40:44Z-
dc.date.available2013-01-28T01:40:44Z-
dc.date.issued1997en_US
dc.identifier.citationPrenatal Diagnosis, 1997, v. 17 n. 3, p. 267-269en_US
dc.identifier.issn0197-3851en_US
dc.identifier.urihttp://hdl.handle.net/10722/180624-
dc.description.abstractHomozygous α-thalassaemia-1 is the commonest cause of hydrops fetalis in South-East Asia. Ultrasonographic features of hydrops fetalis were said to be evident only after 20 weeks of gestation. We studied 111 pregnancies at risk of homozygous α-thalassaemia-1 at 12-14 gestational weeks and 101 pregnancies at 17-18 weeks by abdominal ultrasound examination. Ultrasonographic features of hydrops fetalis were seen in 3 out of 44 pregnancies affected by homozygous α-thalassaemia-1 at 12-14 weeks [7 per cent; 95 per cent confidence interval (CI) 1-19 per cent] and in 7 out of 21 affected pregnancies at 17-18 weeks (33 per cent; 95 per cent CI 15-57 per cent). In conclusion, homozygous α-thalassaemia-1 can cause hydrops fetalis in the early second trimester. It should constitute one of the differential diagnoses in the work-up of second-trimester hydrops fetalis.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252en_US
dc.relation.ispartofPrenatal Diagnosisen_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshHomozygoteen_US
dc.subject.meshHumansen_US
dc.subject.meshHydrops Fetalis - Etiology - Ultrasonographyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Hematologic - Ultrasonographyen_US
dc.subject.meshPregnancy Trimester, Firsten_US
dc.subject.meshPregnancy Trimester, Seconden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshAlpha-Thalassemia - Complications - Embryology - Genetics - Ultrasonographyen_US
dc.titleSecond-trimester hydrops fetalis in pregnancies affected by homozygous α-thalassaemia-1en_US
dc.typeArticleen_US
dc.identifier.emailTang, MHY: mhytang@hkucc.hku.hken_US
dc.identifier.authorityTang, MHY=rp01701en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/(SICI)1097-0223(199703)17:3<267::AID-PD54>3.0.CO;2-#en_US
dc.identifier.pmid9110371-
dc.identifier.scopuseid_2-s2.0-0030940684en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030940684&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume17en_US
dc.identifier.issue3en_US
dc.identifier.spage267en_US
dc.identifier.epage269en_US
dc.identifier.isiWOS:A1997WQ94300005-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLam, YH=7202563903en_US
dc.identifier.scopusauthoridGhosh, A=7403963873en_US
dc.identifier.scopusauthoridTang, MHY=8943401300en_US
dc.identifier.scopusauthoridLee, CP=7410149538en_US
dc.identifier.scopusauthoridSin, SY=7006553270en_US

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