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Article: Dietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers

TitleDietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers
Authors
KeywordsClinical trial
Cortisol
Endurance
Herbal supplement
Maximal oxygen uptake
Testosterone
Issue Date2009
Citation
Chinese Journal Of Integrative Medicine, 2009, v. 15 n. 3, p. 177-183 How to Cite?
AbstractObjective: To determine whether the ingestion of a herbal supplement called Rhodiola-Gingko Capsule (RGC) would enhance the endurance performance of healthy volunteers and change relevant hormones in a favorable manner. Methods: Seventy healthy male volunteers (age ranges from 18 to 22 years old) were randomly assigned to RGC group (35 cases, each capsule containing 270 mg herbal extracts, 4 capsules per day) or placebo group (35 cases, equivalent placebo preparation) for 7 weeks using computer-produced digital random method. The endurance performance, serum testosterone and cortisol levels were measured at the baseline and the endpoint. Results: Sixty-seven subjects (34 in the RGC group and 33 in the placebo group) completed a 7-week treatment. The RGC group displayed a significantly greater baseline-to-endpoint increase in maximal oxygen uptake (VO2max) than placebo group in both absolute (P=0.020) and relative values (P=0.023). At the endpoint, the serum cortisol level was unchanged in the RGC group compared with the baseline, but it was significantly elevated in the placebo group (P<0.05). The endpoint ratio of testosterone to cortisol, a surrogate for overtraining and fatigue in endurance exercises, was also indifferent compared with the baseline in the RGC group, but significantly decreased in the placebo group (P<0.05). Conclusion: The combined herbal supplement of Rhodiola and Gingko could improve the endurance performance by increasing oxygen consumption and protecting against fatigue.
Persistent Identifierhttp://hdl.handle.net/10722/179451
ISSN
2019 Impact Factor: 1.545
2015 SCImago Journal Rankings: 0.454
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, ZJen_US
dc.contributor.authorTong, Yen_US
dc.contributor.authorZou, Jen_US
dc.contributor.authorChen, PJen_US
dc.contributor.authorYu, DHen_US
dc.date.accessioned2012-12-19T09:56:41Z-
dc.date.available2012-12-19T09:56:41Z-
dc.date.issued2009en_US
dc.identifier.citationChinese Journal Of Integrative Medicine, 2009, v. 15 n. 3, p. 177-183en_US
dc.identifier.issn1672-0415en_US
dc.identifier.urihttp://hdl.handle.net/10722/179451-
dc.description.abstractObjective: To determine whether the ingestion of a herbal supplement called Rhodiola-Gingko Capsule (RGC) would enhance the endurance performance of healthy volunteers and change relevant hormones in a favorable manner. Methods: Seventy healthy male volunteers (age ranges from 18 to 22 years old) were randomly assigned to RGC group (35 cases, each capsule containing 270 mg herbal extracts, 4 capsules per day) or placebo group (35 cases, equivalent placebo preparation) for 7 weeks using computer-produced digital random method. The endurance performance, serum testosterone and cortisol levels were measured at the baseline and the endpoint. Results: Sixty-seven subjects (34 in the RGC group and 33 in the placebo group) completed a 7-week treatment. The RGC group displayed a significantly greater baseline-to-endpoint increase in maximal oxygen uptake (VO2max) than placebo group in both absolute (P=0.020) and relative values (P=0.023). At the endpoint, the serum cortisol level was unchanged in the RGC group compared with the baseline, but it was significantly elevated in the placebo group (P<0.05). The endpoint ratio of testosterone to cortisol, a surrogate for overtraining and fatigue in endurance exercises, was also indifferent compared with the baseline in the RGC group, but significantly decreased in the placebo group (P<0.05). Conclusion: The combined herbal supplement of Rhodiola and Gingko could improve the endurance performance by increasing oxygen consumption and protecting against fatigue.en_US
dc.languageengen_US
dc.relation.ispartofChinese Journal of Integrative Medicineen_US
dc.subjectClinical trial-
dc.subjectCortisol-
dc.subjectEndurance-
dc.subjectHerbal supplement-
dc.subjectMaximal oxygen uptake-
dc.subjectTestosterone-
dc.subject.meshAdolescenten_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshDrugs, Chinese Herbal - Administration & Dosage - Adverse Effectsen_US
dc.subject.meshFatigue - Drug Therapyen_US
dc.subject.meshGinkgo Bilobaen_US
dc.subject.meshHumansen_US
dc.subject.meshHydrocortisone - Blooden_US
dc.subject.meshIntegrative Medicineen_US
dc.subject.meshMaleen_US
dc.subject.meshOxygen Consumption - Drug Effectsen_US
dc.subject.meshPhysical Endurance - Drug Effectsen_US
dc.subject.meshPlacebosen_US
dc.subject.meshRhodiolaen_US
dc.subject.meshTestosterone - Blooden_US
dc.subject.meshYoung Adulten_US
dc.titleDietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteersen_US
dc.typeArticleen_US
dc.identifier.emailZhang, ZJ: zhangzj@hkucc.hku.hken_US
dc.identifier.emailTong, Y: tongyao@hku.hken_US
dc.identifier.authorityZhang, ZJ=rp01297en_US
dc.identifier.authorityTong, Y=rp00509en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s11655-009-0177-xen_US
dc.identifier.pmid19568709-
dc.identifier.scopuseid_2-s2.0-67650470975en_US
dc.identifier.hkuros160156-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67650470975&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume15en_US
dc.identifier.issue3en_US
dc.identifier.spage177en_US
dc.identifier.epage183en_US
dc.identifier.isiWOS:000266755800005-
dc.identifier.scopusauthoridZhang, ZJ=8061473900en_US
dc.identifier.scopusauthoridTong, Y=9045384000en_US
dc.identifier.scopusauthoridZou, J=35217440500en_US
dc.identifier.scopusauthoridChen, PJ=26659806300en_US
dc.identifier.scopusauthoridYu, DH=23994607600en_US
dc.identifier.citeulike5113752-
dc.identifier.issnl1672-0415-

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