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- Publisher Website: 10.1093/molbev/msh106
- Scopus: eid_2-s2.0-3242785814
- PMID: 15014139
- WOS: WOS:000222961400002
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Article: Structure and molecular phylogeny of sasA genes in cyanobacteria: Insights into evolution of the prokaryotic circadian system
Title | Structure and molecular phylogeny of sasA genes in cyanobacteria: Insights into evolution of the prokaryotic circadian system |
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Authors | |
Keywords | Circadian system Cyanobacteria Evolution Prokaryotes sasA |
Issue Date | 2004 |
Publisher | Oxford University Press. The Journal's web site is located at http://mbe.oxfordjournals.org/ |
Citation | Molecular Biology And Evolution, 2004, v. 21 n. 8, p. 1468-1476 How to Cite? |
Abstract | Cyanobacteria are the simplest organisms known to have a circadian system. In addition to the three well-studied kai genes, kaiA, kaiB, and kaiC, an important element of this system is a two-component sensory transduction histidine kinase sasA. Using publicly available data of complete prokaryotic genomes, we performed structural and phylogenetic analyses of the sasA genes. Results show that this gene has a triple-domain structure, and the domains are under different selective constraints. The sasA gene originated in cyanobacteria probably through the fusion of the ancestral kaiB gene with a double-domain, two-component sensory transduction histidine kinase. The results of the phylogenetic analyses suggest that sasA emerged before the kaiA gene, about 3,000-2,500 MYA, and has evolved in parallel with the evolution of the kaiBC cluster. The observed concordant patterns of the sasA and kaiBC evolution suggest that these genes might compose an ancient KaiBC-SasA-based circadian system, without the kaiA gene, and that such a system still exists in some unicellular cyanobacteria. |
Persistent Identifier | http://hdl.handle.net/10722/178929 |
ISSN | 2021 Impact Factor: 8.800 2020 SCImago Journal Rankings: 6.637 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dvornyk, V | en_US |
dc.contributor.author | Deng, HW | en_US |
dc.contributor.author | Nevo, E | en_US |
dc.date.accessioned | 2012-12-19T09:50:48Z | - |
dc.date.available | 2012-12-19T09:50:48Z | - |
dc.date.issued | 2004 | en_US |
dc.identifier.citation | Molecular Biology And Evolution, 2004, v. 21 n. 8, p. 1468-1476 | en_US |
dc.identifier.issn | 0737-4038 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/178929 | - |
dc.description.abstract | Cyanobacteria are the simplest organisms known to have a circadian system. In addition to the three well-studied kai genes, kaiA, kaiB, and kaiC, an important element of this system is a two-component sensory transduction histidine kinase sasA. Using publicly available data of complete prokaryotic genomes, we performed structural and phylogenetic analyses of the sasA genes. Results show that this gene has a triple-domain structure, and the domains are under different selective constraints. The sasA gene originated in cyanobacteria probably through the fusion of the ancestral kaiB gene with a double-domain, two-component sensory transduction histidine kinase. The results of the phylogenetic analyses suggest that sasA emerged before the kaiA gene, about 3,000-2,500 MYA, and has evolved in parallel with the evolution of the kaiBC cluster. The observed concordant patterns of the sasA and kaiBC evolution suggest that these genes might compose an ancient KaiBC-SasA-based circadian system, without the kaiA gene, and that such a system still exists in some unicellular cyanobacteria. | en_US |
dc.language | eng | en_US |
dc.publisher | Oxford University Press. The Journal's web site is located at http://mbe.oxfordjournals.org/ | en_US |
dc.relation.ispartof | Molecular Biology and Evolution | en_US |
dc.subject | Circadian system | - |
dc.subject | Cyanobacteria | - |
dc.subject | Evolution | - |
dc.subject | Prokaryotes | - |
dc.subject | sasA | - |
dc.subject.mesh | Amino Acid Sequence | en_US |
dc.subject.mesh | Bacterial Proteins - Genetics | en_US |
dc.subject.mesh | Circadian Rhythm - Genetics | en_US |
dc.subject.mesh | Computational Biology | en_US |
dc.subject.mesh | Cyanobacteria - Genetics | en_US |
dc.subject.mesh | Evolution, Molecular | en_US |
dc.subject.mesh | Gene Expression Regulation, Bacterial - Genetics | en_US |
dc.subject.mesh | Molecular Sequence Data | en_US |
dc.subject.mesh | Phosphotransferases - Genetics | en_US |
dc.subject.mesh | Phylogeny | en_US |
dc.subject.mesh | Promoter Regions, Genetic | en_US |
dc.subject.mesh | Synechococcus - Genetics | en_US |
dc.title | Structure and molecular phylogeny of sasA genes in cyanobacteria: Insights into evolution of the prokaryotic circadian system | en_US |
dc.type | Article | en_US |
dc.identifier.email | Dvornyk, V: dvornyk@hku.hk | en_US |
dc.identifier.authority | Dvornyk, V=rp00693 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1093/molbev/msh106 | en_US |
dc.identifier.pmid | 15014139 | - |
dc.identifier.scopus | eid_2-s2.0-3242785814 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-3242785814&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 21 | en_US |
dc.identifier.issue | 8 | en_US |
dc.identifier.spage | 1468 | en_US |
dc.identifier.epage | 1476 | en_US |
dc.identifier.isi | WOS:000222961400002 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Dvornyk, V=6701789786 | en_US |
dc.identifier.scopusauthorid | Deng, HW=7401775190 | en_US |
dc.identifier.scopusauthorid | Nevo, E=7102721093 | en_US |
dc.identifier.issnl | 0737-4038 | - |